Results 131 to 140 of about 44,405 (256)

Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum [PDF]

open access: yes, 2005
In contrast to the common and genetically complex senile form of Alzheimer's disease (AD), the molecular genetic dissection of inherited presenile dementias has given important mechanistic insights into the pathogenesis of degenerative brain disease ...
Cruts, Marc   +5 more
core   +1 more source

Behavioral and Neurophysiological Effects of Transdermal Rotigotine in Atypical Parkinsonism [PDF]

open access: yes, 2014
Effective therapies for the so-called atypical parkinsonian syndrome (APS) such as multiple system atrophy (MSA), progressive supranuclear palsy (PSP), or corticobasal syndrome (CBS) are not available.
Davide Vito Moretti   +3 more
core   +2 more sources

Diagnostic Value of Bedside Eye Movement Examination in Movement Disorders

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Eloísa Bittencurt Thomaz de Assis   +4 more
wiley   +1 more source

Sialylation patterns in cerebral amyloid angiopathy

open access: yesBrain Pathology, EarlyView.
This study is the first to localize and evaluate sialylation modifications in the context of Alzheimer's Disease and Cerebral Amyloid Angiopathy, revealing a unique disease‐specific increase in intravascular sialylation. Abstract Glycosylation is the most common form of post‐translational modification in the brain and becomes significantly altered in ...
Caitlyn Fastenau   +8 more
wiley   +1 more source

Challenges with the differential diagnosis of progressive supranuclear palsy and Parkinson’s disease

open access: yesАнналы клинической и экспериментальной неврологии, 2017
Progressive supranuclear palsy (PSP) is a severe old-age neurodegenerativedisease that is characterized by pronouncedclinical polymorphism and has different phenotypes.
R. V. Magzhanov   +5 more
doaj   +1 more source

Early and Differential Diagnosis of Dementia and Mild Cognitive Impairment Design and Cohort Baseline Characteristics of the German Dementia Competence Network [PDF]

open access: yes, 2009
Background: The German Dementia Competence Network (DCN) has established procedures for standardized multicenter acquisition of clinical, biological and imaging data, for centralized data management, and for the evaluation of new treatments.
Frölich, Lutz   +21 more
core   +1 more source

3D imaging of neuronal inclusions and protein aggregates in human neurodegeneration by multiscale x‐ray phase‐contrast tomography

open access: yesBrain Pathology, EarlyView.
x‐ray phase‐contrast tomography enabled three‐dimensional, label‐free visualization and quantification of protein aggregates in neurodegenerative diseases with isotropic submicrometer resolution. The study revealed distinct electron density patterns in Lewy bodies, Hirano bodies, granulovacuolar degeneration, and amyloid plaques, highlighting their ...
Jonas Franz   +9 more
wiley   +1 more source

Diplopia and eye movement disorders.

open access: yes, 2004
Published ...
Danchaivijitr, C, Kennard, C
core   +2 more sources

Longitudinal assessment of reflexive and volitional saccades in Niemann-Pick Type C disease during treatment with miglustat [PDF]

open access: yes, 2015
Peer reviewedPublisher ...
Abel, Larry A   +4 more
core   +3 more sources

Alzheimer's disease and mixed pathologies as a hidden contributor to fatal hypothermia: A large‐scale forensic autopsy‐based study

open access: yesBrain Pathology, EarlyView.
We investigated neuropathological manifestations of hypothermia in 168 cases. Patients aged 65 years or more constituted 80% of the total cohort. Alzheimer's disease was the most common comorbidity, affecting 40% of all patients. Abstract There is a paucity of autopsy‐based studies providing detailed neuropathological characteristics of fatal ...
Shojiro Ichimata   +2 more
wiley   +1 more source

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