Results 101 to 110 of about 59,059 (254)

A child of Williams-Beuren syndrome for inguinal hernia repair: Perioperative management concerns

The Indian Anaesthetists' Forum, 2016
Williams-Beuren syndrome, commonly known as Williams syndrome (WS), is a multi-organ disorder. The principal anomalies of the syndrome are developmental delay, unusual craniofacial dysmorphic features, and cardiovascular anomalies such as valvular or ...
Sangeeta Deka, Jyotirmoy Das, Sangeeta Khanna, Yatin Mehta, Meera Luthra   +4 more
doaj   +1 more source

A Case of William’s Syndrome in a Ugandan Child: A Feasible Diagnosis Even in a Low-Resource Setting

Children, 2021
Background: Williams–Beuren syndrome (WS) is a rare, complex, congenital developmental disorder including cardiovascular manifestations, intellectual disability and a peculiar cognitive and behavior profile.
Massimo Mapelli, Paola Zagni, Valeria Calbi, Aliku Twalib, Roberto Ferrara, Piergiuseppe Agostoni   +5 more
doaj   +1 more source

Copy number variations: The potential association genetic cause in severe cardiovascular diseases with unknown aetiology

Journal of Cellular and Molecular Medicine, Volume 28, Issue 12, June 2024.
Abstract Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. While both genetic and environmental factors significantly contribute to the pathogenesis of CVDs, recent advancements in genetic technology have further emphasized the significance of genetic factors in CVDs.
Niloofar Naderi, MohammadHossein MozafaryBazargany, Majid Maleki, Samira Kalayinia   +3 more
wiley   +1 more source

Cardiac outcomes in adults with supravalvar aortic stenosis [PDF]

, 2017
Aims Supravalvar aortic stenosis is a rare form of left ventricular outflow tract obstruction that is often progressive in childhood. Little data are available on outcomes in the adult population.
Beauchesne, Luc, Deanfield, John E., Golovatyuk, Vasilisa, Greutmann, Matthias, Hoffmann, Andreas, Kaemmerer, Harald, Mebus, Siegrun, Oechslin, Erwin N., Salehian, Omid, Schuler, Pia K., Sharma, Nakul Chander, Silversides, Candice K., Tobler, Daniel, Vonder Muhll, Isabelle   +13 more
core  

Vascular disease modeling using induced pluripotent stem cells: Focus in Hutchinson-Gilford Progeria Syndrome [PDF]

, 2016
Transparency document related to this article can be found online at http://dx.doi.org/10.1016/j.bbrc.2015.10.014Induced pluripotent stem cells (iPSCs) represent today an invaluable tool to create disease cell models for modeling and drug screening ...
Ferreira, L., Pereira, P., Praça, C., Rosa, S. C.   +3 more
core   +1 more source

A case series of rare pathologies of the aorta and the aortic arch in adolescents and younger adults: Transfer of experience for an individualized approach

Frontiers in Cardiovascular Medicine, 2022
ObjectiveWhile aneurysm of the aortic root, interrupted aortic arch, and aortic coarctation are the most frequent aortic diseases in adolescents and younger adults, there are a number of rare pathologies of the thoracic aorta that need individualized ...
Thierry Carrel, Thierry Carrel, Thierry Carrel, Islamjan Sharipov, Adham Jalilov, Juri Sromicki, Juri Sromicki, Juri Sromicki, Paul Robert Vogt, Paul Robert Vogt, Paul Robert Vogt   +10 more
doaj   +1 more source

Progress of Congenital Heart Disease: The Team Approach as It Includes the Anesthesiologist [PDF]

, 1972
Advances in cardiac surgery have been great in the last 30 years, but further progress is anticipated, especially in infants. A cooperative effort involving referring physicians, pediatric cardiologists, physiologists, anesthesiologists, surgeons, and ...
McCue, Carolyn M.
core   +1 more source

Myocardial proteome changes in aortic stenosis rats subjected to long‐term aerobic exercise

Journal of Cellular Physiology, Volume 239, Issue 4, April 2024.
Abstract The effects of exercise training (ET) on the heart of aortic stenosis (AS) rats are controversial and the mechanisms involved in alterations induced by ET have been poorly clarified. In this study, we analyzed the myocardial proteome to identify proteins modulated by moderate‐intensity aerobic ET in rats with chronic supravalvular AS.
Gustavo Augusto Ferreira Mota, Sérgio Luiz Borges de Souza, Danielle Fernandes Vileigas, Vitor Loureiro da Silva, Paula Grippa Sant'Ana, Licia Carla da Silva Costa, Carlos Roberto Padovani, Silméia Garcia Zanatti Bazan, Marília Afonso Rabelo Buzalaf, Lucilene Delazari dos Santos, Marina Politi Okoshi, Mariana Gatto, Antonio Carlos Cicogna   +12 more
wiley   +1 more source

JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency

The Journal of Clinical Investigation, 2022
Obstructive arterial diseases, including supravalvular aortic stenosis (SVAS), atherosclerosis, and restenosis, share 2 important features: an abnormal or disrupted elastic lamellae structure and excessive smooth muscle cells (SMCs).
Jui M. Dave, Raja Chakraborty, Aglaia Ntokou, Junichi Saito, Fatima Z. Saddouk, Zhonghui Feng, Ashish Misra, George Tellides, Robert K. Riemer, Zsolt Urban, Caroline Kinnear, James Ellis, Seema Mital, Robert Mecham, Kathleen A. Martin, Daniel M. Greif   +15 more
doaj   +1 more source

Integrin β3 inhibition is a therapeutic strategy for supravalvular aortic stenosis. [PDF]

J Exp Med, 2016
Misra et al. elucidate the origin of smooth muscle cells involved in supravalvular aortic stenosis and identify the integrin β3 pathway as a therapeutic target in this disease.
Misra A, Sheikh AQ, Kumar A, Luo J, Zhang J, Hinton RB, Smoot L, Kaplan P, Urban Z, Qyang Y, Tellides G, Greif DM.   +11 more
europepmc   +2 more sources