Results 91 to 100 of about 218,382 (265)

Increased circulating progranulin is not sufficient to induce cardiac dysfunction or supraventricular arrhythmia. [PDF]

open access: yesSci Rep, 2023
McElhanon KE   +4 more
europepmc   +1 more source

Repolarization adaptation to rapid change in heart rate in human models – a review

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This review focuses on non‐invasive assessment of repolarization duration and dispersion (heterogeneity) adaptation to change in heart rate (HR). HR was increased incrementally by left atrial pacing during an electrophysiology (EP) study and by a bolus injection of atropine and in a step up/down fashion by repeated right atrial ...
Lennart Bergfeldt   +5 more
wiley   +1 more source

A Randomized Trial on the Combined Effect of Ponesimod and Propranolol on Heart Rate, Cardiac Safety, and Pharmacokinetics in Healthy Adults

open access: yesClinical and Translational Science, Volume 18, Issue 9, September 2025.
ABSTRACT The objective of this phase 1 study was to evaluate the pharmacokinetics (PK), pharmacodynamics, and cardiac effect following administration of ponesimod (a selective sphingosine‐1‐phosphate receptor modulator) and propranolol in healthy adults. In treatment period (TP) 1, participants received ponesimod (2 mg).
Sivi Ouwerkerk‐Mahadevan   +10 more
wiley   +1 more source

Retrospective Study Evaluating Outcomes Following Palliative Radiotherapy With or Without Chemotherapy for Dogs With Presumed Cardiac Hemangiosarcoma

open access: yesVeterinary and Comparative Oncology, Volume 23, Issue 3, Page 432-441, September 2025.
ABSTRACT Canine cardiac hemangiosarcoma (cHSA) represents a complex clinical challenge in that those afflicted have an acute risk of death due to cardiac tamponade and high morbidity and mortality given the frequency of metastasis. Previous studies show that radiation therapy (RT) can decrease the risk of tamponade; however, an optimal approach has yet
Cory N. Wakamatsu   +4 more
wiley   +1 more source

Coexistence of Atrioventricular Nodal Reentrant Tachycardia and Idiopathic Left Ventricular Outflow-Tract Tachycardia [PDF]

open access: yes, 2005
Double tachycardia is a relatively rare condition. We describe a 21 year old woman with history of frequent palpitations. In one of these episodes, she had wide complex tachycardia with right bundle branch and inferior axis morphology.
Arya, Arash   +6 more
core   +2 more sources

Seasonal variations in ventricular repolarization and tachyarrhythmias in hibernating brown bears (Ursus arctos arctos)

open access: yesPhysiological Reports, Volume 13, Issue 17, September 2025.
Abstract In humans, hypothermia prolongs ventricular repolarization and associates with sustained ventricular tachyarrhythmias. In bears, body temperature drops during hibernation similar to moderate human hypothermia, yet they rarely face fatal outcomes during the winter. This suggests protective adaptations in bear electrophysiology.
Lucas Alexander Lindberg   +6 more
wiley   +1 more source

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