Results 71 to 80 of about 11,163 (261)

The Drive for Judicial Supremacy

open access: yes, 2012
Great efforts at judicial reform have been made in Central-Eastern European countries (CEE) over the last 20 years. The earliest reforms were driven by the domestic need for foreign investment and the security of contracts and private property rights which investors expect.
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

SUPREMACY OF THE CONSTITUTION THEORETICAL AND PRACTICAL CONSIDERATIONS [PDF]

open access: yesChallenges of the Knowledge Society, 2018
Regarding the term of supremacy of the constitution, many authors consider that it is notorious and therefore does not require a special scientific analysis.
Marius ANDREESCU, Claudia ANDREESCU
doaj  

Constitutional Supremacy: National Constitutions vs. European Law

open access: yesAustralian and New Zealand Journal of European Studies, 2011
CESAA 18TH ANNUAL EUROPE ESSAY COMPETITION 2010 - Postgraduate winner: Vanessa McGlynn, University of New South Wales Almost 50 years after the European Court of Justice clearly established the supremacy of Community law, the question regarding the ...
Vanessa McGlynn
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

White Supremacy: America's Original Sin?

open access: yesThe Journal of Studies in Language, Culture and Society, 2021
Writing about white supremacy in the US may sound unoriginal and trite but I believe it is way too important to continue studying it with regard to its relevancy and the challenges it continues to pause to justice, equity and harmony in the American ...
Papa Malick BA
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

White Supremacy in the Nordic Countries: Erasing Racism and Indigenous Voices

open access: yesGenealogy
Recent scholarship has called for greater attention to white supremacy. This is closely linked to broader efforts to foreground the structural and institutional dimensions of racism.
Kristín Loftsdóttir
doaj   +1 more source

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