Results 101 to 110 of about 12,379 (285)
Advanced Science, EarlyView.In non‐tumorous lung tissues, FOXN3 promotes the transcriptional activation of p53 by facilitating its recruitment to target promoters, thereby suppressing lung tumorigenesis through activation of the p53 signaling pathway. Conversely, in lung adenocarcinoma tissues, hyperphosphorylated FOXN3 dissociates from the promoters of p53‐responsive genes and ...
Jinjin Yu +16 more
wiley +1 more source
Le finalità e i postulati del bilancio nel nuovo OIC 11 [PDF]
, 2018 L’Organismo Italiano di Contabilità ha pubblicato una nuova versione dell’OIC 11, Finalità e postulati del bilancio d’esercizio. La revisione del principio è l’occasione per chiarire alcuni punti essenziali della disciplina contabile nazionale che non
Alessandro Sura
core
The Struggle for Territorial Control in Colombia: An Analysis of the Dynamics of the Armed Conflict
Ecos de Economía, 2015 This paper reviews the literature on the theory of armed conflict and examines its application to the insurgents´ struggle with the State for political and territorial control in Colombia during 1999-2010.
Juan Fernando Henao Duque +2 more
doaj +1 more source
Advanced Science, EarlyView.In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang +19 more
wiley +1 more source
Sura | صورة: Egypte door een Belgische lens [PDF]
, 2023 In het begin van de 20e eeuw ondernamen de Belgische egyptoloog Jean Capart en zijn medewerkers verschillende reizen naar Egypte. Met een passie voor fotografie documenteerden zij het land aan de Nijl in al zijn facetten.
De Meyer, Marleen +3 more
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Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Advanced Science, EarlyView.Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source
Il trattamento contabile delle operazioni in valuta ai sensi del nuovo OIC 26 [PDF]
, 2014 L’Organismo Italiano di Contabilità (OIC) ha pubblicato una nuova versione dell’OIC 26 Operazioni, attività e passività in valuta estera. Con il nuovo principio, si è riformulata, per meglio chiarirne gli aspetti applicativi, la disciplina relativa ...
SURA, ALESSANDRO
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Advanced Science, EarlyView.A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu +12 more
wiley +1 more source
Il nuovo principio OIC 15 (Crediti) si avvicina alle regole dei principi contabili internazionali [PDF]
, 2014 L’OIC ha pubblicato il nuovo principio contabile sui crediti OIC 15. Il principio introduce novità di rilevo sul tema della cancellazione dei crediti deal bilancio, richiedendo come condizione necessaria per lo stralcio dal bilancio il trasferimento dei
SURA, ALESSANDRO
core
Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response
Advanced Science, EarlyView.This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du +10 more
wiley +1 more source