Forecasting <i>in vivo</i> pharmacokinetics of metformin HCl floating beads using Gastroplus® PBPK. [PDF]
Mahmood SZ +2 more
europepmc +1 more source
The improvement of proprioceptive function after ACLR is related to the optimization of spatiotemporal dynamics of SM, CC, DM, CB and VI functional networks. Rehabilitation optimization can incorporate visual–cognitive dual‐task exercises. Abstract Purpose In this study, we aimed to examine the dynamic functional network connectivity (dFNC) patterns ...
Xiaoyun Zhuang +7 more
wiley +1 more source
Soleus subtendon elongation is reduced by individual suturing of Achilles subtendons after rupture
The findings supported the hypothesis that individually suturing soleus and gastrocnemius subtendons reduces soleus subtendon elongation by approximately 50% compared with the standard technique 1 week after Achilles tendon repair. Although both subtendons elongated over 6 months, soleus elongation remained significantly lower with individual suturing,
Rasmus Kramer Mikkelsen +7 more
wiley +1 more source
Baseline household income is associated with severity and course of severe mental illness. [PDF]
Valencia-Arango JP +17 more
europepmc +1 more source
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
Implementation of Polygenic Risk Stratification and Genomic Counseling in Colombia: An Embedded Mixed-Methods Study. [PDF]
Buitrago CA +9 more
europepmc +1 more source
Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva +23 more
wiley +1 more source
Burden and impact of pulmonary embolism in young adults hospitalized with sarcoidosis: Underreported data from nationwide analysis (2016-2020). [PDF]
Bhanushali AK +8 more
europepmc +1 more source
Pasteurella lipoprotein E interacts with host ABCF2 to facilitate adhesion and cell apoptosis
Abstract Pasteurella multocida can cause serious diseases in many animal species and humans, yet the mechanisms of its pathogenesis remain to be elucidated. In this study, we found that the lipoprotein E (PlpE) of P. multocida contributed to bacterial adhesion to host cells.
Yuyao Shang +8 more
wiley +1 more source
Molecular background of Philadelphia chromosome dependent enhancement of cellular growth and tyrosine kinase inhibitor sensitivity. [PDF]
Hossain MF +12 more
europepmc +1 more source

