Results 51 to 60 of about 22,517 (202)

CD31+ Cell Enrichment Enhances Therapeutic Effects of Stromal Vascular Fraction in Experimental Primary Osteoarthritis: A Preclinical Study in the Dunkin Hartley Guinea Pig Model

Advanced Science, EarlyView.
Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou, Tobias Winkler, Bin Chen, Marta Grzeski, Yilong Yang, Florian N. Fleckenstein, Dominik Geisel, Alexander Hildebrandt, Daniela Aschenbrenner, Marie Agatha Mohn, Benjamin Claass, January Weiner 3rd, Sven Geissler, Georg N. Duda, Søren P. Sheikh, Oliver Klein, Tazio Maleitzke   +16 more
wiley   +1 more source

Aberrant Changes in Cortical Complexity in Right-Onset Versus Left-Onset Parkinson’s Disease in Early-Stage

Frontiers in Aging Neuroscience, 2021
There is increasing evidence to show that motor symptom lateralization in Parkinson’s disease (PD) is linked to non-motor features, progression, and prognosis of the disease.
Lin Zhang, Qin Shen, Haiyan Liao, Junli Li, Tianyu Wang, Tianyu Wang, Yuheng Zi, Fan Zhou, Chendie Song, Zhenni Mao, Min Wang, Sainan Cai, Changlian Tan   +12 more
doaj   +1 more source

DDSurfer: A Weakly‐Supervised Dual‐Stream Deep Learning Framework for Cortical Surface Reconstruction From Diffusion MRI

Advanced Science, EarlyView.
DDSurfer reconstructs cortical surfaces directly from diffusion MRI without requiring T1‐weighted scans. By fusing complementary microstructural features and learning diffeomorphic deformations, it efficiently generates accurate white matter and pial surfaces, improving geometric fidelity and morphometric reliability across datasets for robust surface ...
Chengjin Li, Wei Zhang, Xi Zhu, Yuqian Chen, Nir A. Sochen, Jarrett Rushmore, Carl‐Fredrik Westin, Yogesh Rathi, Lauren J. O'Donnell, Ofer Pasternak, Fan Zhang   +10 more
wiley   +1 more source

Structural changes in the gray matter of the contralateral hemisphere and prognosis of motor function in children with pharmacoresistant epilepsy before and after hemispherotomy

NeuroImage
Objective: Hemispherotomy (HS) is an effective treatment option to control seizures for children with pharmacoresistant epilepsy. We aimed to explore the alteration of the gray matter structure before and after surgery and identify the specific brain ...
Yilin Zhao, Dezhi Cao, Fengjun Zhu, Li Chen, Zeshi Tan, Turong Chen, Hongwu Zeng   +6 more
doaj   +1 more source

Cortical Thickness Changes in Chronic Ketamine Users

Frontiers in Psychiatry, 2021
Background: Previous studies have examined the effects of long-term ketamine use on gray matter volume. But it is unclear whether chronic ketamine use alters cortical thickness and whether cortical thickness changes in chronic ketamine users are ...
Jun Zhong, Huawang Wu, Fengchun Wu, Hongbo He, Zhaohua Zhang, Jiaxin Huang, Penghui Cao, Ni Fan   +7 more
doaj   +1 more source

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

Advanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma, Lucinda A. E. Evans, Lucie E. Bourne, Jishizhan Chen, Alissa L. Parmenter, Joseph Brunet, Kamel Madi, Sebastian Marussi, Andrew A. Pitsillides, Peter D. Lee, Katherine A. Staines   +10 more
wiley   +1 more source

Cortical Areas Associated With Multisensory Integration Showing Altered Morphology and Functional Connectivity in Relation to Reduced Life Quality in Vestibular Migraine

Frontiers in Human Neuroscience, 2021
Background: Increasing evidence suggests that the temporal and parietal lobes are associated with multisensory integration and vestibular migraine.
Xia Zhe, Li Chen, Dongsheng Zhang, Min Tang, Jie Gao, Kai Ai, Weijun Liu, Xiaoyan Lei, Xiaoling Zhang   +8 more
doaj   +1 more source

Organ Shape Modeling Based on the Laplacian Deformation Framework for Surface-Based Morphometry Studies [PDF]

Journal of Computing Science and Engineering, 2012
Recently, shape analysis of human organs has achieved much attention, owing to its potential to localize structural abnormalities. For a group-wise shape analysis, it is important to accurately restore the shape of a target structure in each subject and to build the inter-subject shape correspondences.
Jae-il Kim, Jinah Park
openaire   +1 more source

Computer Vision Pipeline for Image Analysis for Freeze‐Fracture Electron Microscopy: Rosette Cellulose Synthase Complexes Case

Advanced Intelligent Discovery, EarlyView.
This paper presents a computer vision (deep learning) pipeline integrating YOLOv8 and YOLOv9 for automated detection, segmentation, and analysis of rosette cellulose synthase complexes in freeze‐fracture electron microscopy images. The study explores curated dataset expansion for model improvement and highlights pipeline accuracy, speed ...
Siri Mudunuri, Leala Carbonneau, Eric M. Roberts, Alison W. Roberts, Candace H. Haigler, Alexey V. Gulyuk, Yaroslava G. Yingling   +6 more
wiley   +1 more source

Associations Between Individual Differences in Mathematical Competencies and Surface Anatomy of the Adult Brain

Frontiers in Human Neuroscience, 2020
Previously conducted structural magnetic resonance imaging (MRI) studies on the neuroanatomical correlates of mathematical abilities and competencies have several methodological limitations.
Alexander E. Heidekum, Stephan E. Vogel, Roland H. Grabner   +2 more
doaj   +1 more source