Results 201 to 210 of about 21,257,823 (383)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Assessing impacts of rainfall intensity and slope gradient on runoff process and dissolved organic carbon loss via surface flow and interflow under simulated rainfall. [PDF]

PLoS One
Xu L, Lu J, Zhang D.
europepmc   +1 more source

Determination of nuclear magnetic resonance surface relaxivity for the macropore system from wood cell lumen [PDF]

Zhi Jin, Yuejin Fu, Qian Chen, Zhen Zeng
openalex   +1 more source

Coupling an Advanced Land Surface–Hydrology Model with the Penn State–NCAR MM5 Modeling System. Part I: Model Implementation and Sensitivity

, 2001
Fei Chen, J. Dudhia
semanticscholar   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Investigating catechol adsorption to the ZnO (101̄0) surface with and without an oxygen vacancies using the DFT-D2 method. [PDF]

RSC Adv
Kamal N, De AK, Shrivastava A, Sinha I.
europepmc   +1 more source

Surface energy and the contact of elastic solids

Proceedings of the Royal Society of London. A. Mathematical and Physical Sciences, 1971
K. Johnson, K. Kendall, A. D. Roberts
semanticscholar   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Optimizing Surface Functionalization for Aptameric Graphene Nanosensors in Undiluted Physiological Media. [PDF]

Sensors (Basel)
Dai W, Wang Z, Yu S, Wen K, Yang Y, Lin Q.   +5 more
europepmc   +1 more source

Daily High-Resolution-Blended Analyses for Sea Surface Temperature

, 2007
R. Reynolds, Thomas M. Smith, Chunying Liu, D. Chelton, K. Casey, M. Schlax   +5 more
semanticscholar   +1 more source