Status and future directions of anti-metastatic cancer nanomedicines for the inhibition of cathepsin L [PDF]
Angiogenesis, tissue invasion and metastasis in the tumour microenvironment are all critical hallmarks of cancer. Upregulation of cathepsin L plays an important role in angiogenesis and metastasis through its ability to degrade the extracellular matrix ...
Pranjol, Md Zahidul I +3 more
core +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
EFFICIENCY OF FOAM-FORMERS USED FOR DRIVING WATER OUT OF WELLS AT LATER STAGES OF FIELD DEVELOPMENT
The article offers the results of a study into the efficiency of various foam-formers (Anionic Surface Active Agents and Nonionic Surface Active Agents) used for removing liquid from boreholes at gas and gas-condensate fields at their latest stages of ...
Ramiz A. Gasumov
doaj
Cytotoxicity evaluation of combination irrigant regimens with MTAD on two different cell lines
Background: Effective management of smear layer ensures adequate clinical success. Use of sodium hypochlorite (NaOCl)/ethylenediaminetetraacetic acid regimen has been the gold standard with limitations.
Manikandan Ravinanthanan +3 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Les esters de sucres : voies de synthèse et potentialités d'utilisation [PDF]
Sugar esters : ways of synthesis and potential applications [a review]. Sugar esters are nonionic surfactants and exhibit relevant properties as structural diversity and environmental and health safety. Their potential applications extend from human food
Blecker C. +7 more
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Role of Surface Active Agents in Transferosome for Systemic Drug Delivery
The recent utilization of transferosomes (a type of vesicular drug-carrier system) has shown promising results in enhancing the transport of drugs through the skin when administered topically.
Mohsin Hussein Abdulameer +2 more
doaj +1 more source
The solubilization of mitochondrial protein by nonionic surface active agents [PDF]
LD2668 .T4 1966 S971Master of ...
Swain, Louis Martin.
core
Looking beyond endotoxin: a comparative study of pyrogen retention by ultrafilters used for the preparation of sterile dialyis fluid [PDF]
Sterile single-use ultrafilters are used in dialysis for the preparation of the substitution fluid given to patients undergoing dialysis treatments with high convective fluid removal.
Brodbeck, Katrin +5 more
core +2 more sources

