Results 71 to 80 of about 162,803 (278)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Cosmicflows-2: I-band Luminosity - HI Linewidth Calibration

open access: yes, 2012
In order to measure distances with minimal systematics using the correlation between galaxy luminosities and rotation rates it is necessary to adhere to a strict and tested recipe.
Bernardi   +35 more
core   +7 more sources

Surface Brightness Fluctuations for constraining the chemical enrichment of massive galaxies [PDF]

open access: yesProceedings of the International Astronomical Union, 2019
AbstractBased on very deep photometry, Surface Brightness Fluctuations (SBF) have been traditionally used to determine galaxy distances. We have recently computed SBF spectra of stellar populations at moderately high resolution, which are fully based on empirical stars.
A. Vazdekis   +5 more
openaire   +3 more sources

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Surface Brightness Fluctuations

open access: yes
The Surface Brightness Fluctuation (SBF) method is a powerful tool for determining distances to early-type galaxies. The method measures the intrinsic variance in a galaxy's surface brightness distribution to determine its distance with an accuracy of about 5%.
Cantiello, Michele, Blakeslee, John P.
openaire   +2 more sources

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash   +6 more
wiley   +1 more source

The impact of main belt asteroids on infrared--submillimetre photometry and source counts [PDF]

open access: yes, 2007
> Among the components of the infrared and submillimetre sky background, the closest layer is the thermal emission of dust particles and minor bodies in the Solar System.
A. Pál   +25 more
core   +2 more sources

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

open access: yesFEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi   +2 more
wiley   +1 more source

Constraining gas motions in the Centaurus cluster using X-ray surface brightness fluctuations and metal diffusion

open access: yes, 2015
We compare two different methods of constraining the characteristic velocity and spatial scales of gas motions in the X-ray bright, nearby Centaurus cluster, using new deep (760ks) Chandra observations.
Fabian, A. C.   +2 more
core   +1 more source

Osmotic pressure‐induced calcium response states

open access: yesFEBS Open Bio, EarlyView.
Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao   +2 more
wiley   +1 more source

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