Results 111 to 120 of about 2,003,861 (306)

Synthesis and properties of magnetically sensitive nanocomposites based on magnetite and gemcitabine

Хімія, фізика та технологія поверхні, 2018
The aim of the work is synthesis of new polyfunctional magnetosensitive nanocomposites (NC) capable of the targeted delivery in the tumors of hepatocellular carcinoma and intrahepatic cholangiocarcinoma of a drug with chemotherapeutic mechanism of ...
A. L. Petranovska, M. V. Abramov, N. M. Opanashchuk, S. P. Turanska, N. V. Kusyak, P. P. Gorbyk   +5 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Synthesis and physico-chemical properties of high-quality expanded graphite

Хімія, фізика та технологія поверхні
The purpose of the work is to establish the possibility of obtaining expanded graphite of high purity (carbon content more than 99.5 % wt.) from flotation-enriched graphite (carbon content 94–97 % wt.) by combining into one process intercalation of ...
Yu. V. Hrebelna, E. M. Demianenko, M. I. Terets, V. V. Lobanov, S. V. Zhuravskyi, O. M. Ignatenko, K. O. Ivanenko, Yu. I. Gornikov, M. T. Kartel, Yu. I. Sementsov   +9 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Mars: The Viking discoveries [PDF]

, 1977
An overview of the Viking Mars probe is presented. The Viking spacecraft is described and a brief history of the earlier observations and exploration of Mars is provided.
French, B. M.
core   +2 more sources

Properties of electrons near a Van Hove singularity

, 2002
The Fermi surface of most hole-doped cuprates is close to a Van Hove singularity at the M point. A two-dimensional electronic system, whose Fermi surface is close to a Van Hove singularity shows a variety of weak coupling instabilities.
Alvarez, B. Valenzuela, Dessau, F. Guinea, Friedel, Friedel, Gofron, González, González, González, Halboth, He, Hlubina, J. González, J.V. Alvarez, King, Labbé, Lee, M.A.H. Vozmediano, Markiewicz, Markiewicz, Matzdorf, Newns, Pickett, Schulz, Shankar, Shen, Valenzuela, Valenzuela   +28 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Surface and Interfacial Chemistry

CHIMIA, 2012
Based on a molecular approach combining controlled surface chemistry, advanced spectroscopic methods, in particular solid-state NMR, and computational chemistry, it is possible to develop single-site species and to control the growth of nanoparticles on supports.
openaire   +4 more sources