Results 141 to 150 of about 363,241 (312)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Effect of Rod-like Structure on Fatigue Life, Short Surface Crack Initiation and Growth Characteristics of Extruded Aluminum Alloy A2024 (Analysis via Modified Linear Elastic Fracture Mechanics). [PDF]
Materials (Basel), 2021 Masuda K +3 more
europepmc +1 more source
A finite element strategy coupling a gradient-enhanced damage model and cohesive cracks for quasi-brittle materials [PDF]
, 2013 A new combined strategy to describe failure of quasi-brittle materials is presented thus allowing the complete description of the process, from initiation of damage to crack propagation.
Rodríguez Ferran, Antonio +1 more
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Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Mixed mode stress intensity factors for semielliptical surface cracks [PDF]
The three-dimensional equations of elasticity are solved for a flat elliptical crack which has nonuniform shear stresses applied to its surfaces. An alternating method is used to determine the mode two and mode three stress intensity factors for a ...
Smith, F. W., Sorensen, D. R.
core +1 more source
Advanced Engineering Materials, EarlyView.Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat +6 more
wiley +1 more source
ANALYSIS ON LIMIT LOAD AND J-INTEGRAL FOR EMBEDDED AND PROPAGATED CRACK PLATES UNDER BIAXIAL LOADING
Jixie qiangdu, 2020 Ligament rupture occurs for embedded crack plate under biaxial loading. Then,embedded crack will propagate as surface crack,through-thickness cracks or extended surface cracks.
LV YuanJun, CHEN Qiong, ZHANG XunLei
doaj
Treatment of singularities in cracked bodies [PDF]
Three-dimensional finite-element analyses of middle-crack tension (M-T) and bend specimens subjected to mode I loadings were performed to study the stress singularity along the crack front.
Raju, I. S., Shivakumar, K. N.
core +1 more source