Results 51 to 60 of about 5,154,367 (254)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Injection‐Related Hazards in the Permian Basin as Characterized by Spaceborne InSAR and In Situ Measurements

open access: yesGeophysical Research Letters
Wastewater injection in Texas has led to leakage at compromised wells and anomalous seismicity. We use Sentinel‐1 Interferometric Synthetic Aperture Radar (InSAR) surface deformation maps and a suite of ground measurements to characterize injection ...
M. S. Zebker   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Investigating Surface Deformation Caused by Excavation of Curved Shield in Upper Soft and Lower Hard Soil

open access: yesFrontiers in Earth Science, 2022
Existing studies on surface deformation prediction consider single soil layers and straight-line excavation when investigating deformation caused by metro shield construction.
Bao-Xin Jia, Bao-Xin Jia, Zong-xian Gao
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

About Development of Representations about Fatigue of Metals at Volume and Surface (Contact) Deformation

open access: yesМеханика машин, механизмов и материалов, 2015
Concept development about fatigue of metals in communication of its integrated characteristic-curve of fatigue is described at volume deformation (and destruction), surface damage (and wear) at contact loading and complex wear-fatigue damage and ...
Leonid A. Sosnovskiy
doaj  

Short‐Term Response to Biologic Therapy in Psoriatic Arthritis Is Not Influenced by Disease Duration at Initiation of Therapy

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to determine whether the short‐term response to biologics in biologic‐naive psoriatic arthritis (PsA) is better in patients initiating biologic treatment early in the disease course. Methods Patients with PsA who started on biologic therapy from the year 2000 to 2025 were included for analysis.
Sung Min Cho   +4 more
wiley   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur   +5 more
wiley   +1 more source

NFDI MatWerk Ontology (MWO): A BFO‐Compliant Ontology for Research Data Management in Materials Science and Engineering

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi   +4 more
wiley   +1 more source

Surface Displacements Monitoring in Cyprus via InSAR and Field Investigation: The Case Studies of Pyrgos-Parekklisia and Pedoulas Villages

open access: yesRemote Sensing
The island of Cyprus is characterised by a complex geological environment as it overlies a boundary zone of three tectonic plates, leading to high seismicity and intensive tectonism.
Stavroula Alatza   +7 more
doaj   +1 more source

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