Results 151 to 160 of about 6,227,293 (250)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Engineering a robust cell-surface display platform in the multi-stress-tolerant yeast Issatchenkia orientalis. [PDF]

Appl Microbiol Biotechnol
Kawahara Y, Nasuno R, Jin YS, Hasunuma T.   +3 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Investigation of system latency detection threshold of virtual auditory display

, 2006
Presented at the 12th International Conference on Auditory Display (ICAD), London, UK, June 20-23, 2006.Presented at the 12th International Conference on Auditory Display (ICAD), London, UK, June 20-23, 2006.It is important in a virtual auditory display (
Iwaya, Y., Suzuki, Y., Yairi, S.
core  

Applying Baculovirus Surface Display Technology for Influenza Cytokine Profiling, Serological Detection and Antiviral Screening. [PDF]

Microb Biotechnol
Cheng LY, Phan ZY, Wang CW, Shen CF, Kuo PC, Li HZ, Chao YC, Tsai CH.   +7 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Yeast surface display-based screening and preliminary characterization of nectin-4-targeting nanobodies for bladder cancer. [PDF]

BMC Biotechnol
Wen J, Wei L, Huang J, Zhou L, Yu J, Cao H, Liang H, Qin M, Cui Z, Chen H, Li Y, Zhao J, Wang F, Liao S, Cheng J.   +14 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Spatial Auditory Displays: Substitution and Complemenarity to Visual Displays

, 2014
Presented at the 20th International Conference on Auditory Display (ICAD2014), June 22-25, 2014, New York, NY.Presented at the 20th International Conference on Auditory Display (ICAD2014), June 22-25, 2014, New York, NY.The primary goal of this research ...
Godfroy-Cooper, Martine, Wenzel, Elizabeth M., Miller, Joel D.   +2 more
core  

Repurposing the bacterial surface display technology for drug delivery. [PDF]

Adv Drug Deliv Rev
Yang S, Yang M, Jennings M, Timek H, Haley AE, Romee R, Li J.   +6 more
europepmc   +1 more source