Results 221 to 230 of about 6,227,293 (250)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Surface display of Nocardia seriolae HRP1 on Bacillus subtilis and its application as live vaccine for largemouth bass. [PDF]

Sci Rep
Zhang F, Li JT, Zhang T, Wang X, Yao Y, Zhou Z.   +5 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Application of phage surface display for the identification of Eu³⁺-binding peptides. [PDF]

Front Bioeng Biotechnol
Techert G, Drobot B, Braun R, Bloss C, Schönberger N, Matys S, Pollmann K, Lederer FL.   +7 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of Borrelia burgdorferi Elp Proteins. [PDF]

Mol Microbiol
Hill N, Matulina LM, MacIntyre C, Hassani MA, Thomas S, Luban M, Ward I, Abdalla A, Leong JM, Garcia BL, Lemieux JE.   +10 more
europepmc   +1 more source

Establishment of a Novel Platform for Developing Oral Vaccines Based on the Surface Display System of Yeast Spores. [PDF]

Int J Mol Sci
Si C, Bai J, Li Y, Li Y, Liu Y, Zhou X, Shi J, Nakanishi H, Li Z.   +8 more
europepmc   +1 more source

A New Bacterial Chassis for Enhanced Surface Display of Recombinant Proteins. [PDF]

Cell Mol Bioeng
Zhang R, Ye N, Wang Z, Yang S, Li J.
europepmc   +1 more source

Protein-cell conjugates as artificial surface display for interfacial biocatalysis. [PDF]

Chem Sci
Wu X, Karring H, Wang Z, Wu C.
europepmc   +1 more source