Results 121 to 130 of about 6,776,803 (247)

Surface photogalvanic effect in Ag2Te

Nature Communications
The bulk photovoltaic effect (BPVE) in non-centrosymmetric materials has attracted significant attention in recent years due to its potential to surpass the Shockley-Queisser limit.
Xiaoyi Xie, Pengliang Leng, Zhenyu Ding, Jinshan Yang, Jingyi Yan, Junchen Zhou, Zihan Li, Linfeng Ai, Xiangyu Cao, Zehao Jia, Yuda Zhang, Minhao Zhao, Wenguang Zhu, Yang Gao, Shaoming Dong, Faxian Xiu   +15 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Bone regenerating effect of surface-functionalized titanium implants with sustained-release characteristics of strontium in ovariectomized rats

International Journal of Nanomedicine, 2016
Vincent Offermanns,1 Ole Zoffmann Andersen,2 Gregor Riede,1 Inge Hald Andersen,3 Klaus Pagh Almtoft,3 Søren Sørensen,3 Michael Sillassen,2 Christian Sloth Jeppesen,3 Michael Rasse,1 Morten Foss,2 Frank Kloss1 1Department of Cranio ...
Offermanns V, Andersen OZ, Riede G, Andersen IH, Almtoft KP, Sørensen S, Sillassen M, Jeppesen CS, Rasse M, Foss M, Kloss F   +10 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Effect of surface roughness on osteogenesis in vitro and osseointegration in vivo of carbon fiber-reinforced polyetheretherketone–nanohydroxyapatite composite

International Journal of Nanomedicine, 2015
Yi Deng,1,2 Xiaochen Liu,2 Anxiu Xu,3 Lixin Wang,4 Zuyuan Luo,2 Yunfei Zheng,1 Feng Deng,3 Jie Wei,5 Zhihui Tang,1 Shicheng Wei1–3 12nd Dental Center, Laboratory of Interdisciplinary Studies, School and Hospital of Stomatology, 2Center ...
Deng Y, Liu X, Xu A, Wang L, Luo Z, Zheng Y, Deng F, Wei J, Tang Z, Wei S   +9 more
doaj  

Free vibration of nanobeams with surface and dynamic flexoelectric effects

Scientific Reports
In this paper, the free vibration of piezoelectric nanobeams considering static flexoelectric, dynamic flexoelectric, and surface effects is studied.
Peng Wang, JiaWei Xu, XiWen Zhang, YingHui Lv   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Prioritizing Forestation in China Through Incorporating Biogeochemical and Local Biogeophysical Effects

Earth's Future
Forestation is a key strategy for climate mitigation in China through its biogeochemical (BGC) effect of ecosystem carbon sequestration. Additionally, the BGC effect of forestation can be either reinforced or counteracted by concurrent biogeophysical ...
Yu Li, Pengyi Zhang, Huanhuan Wang, Hui Ma, Jie Zhao, Mengyang Xu, Mengyu Wang, Chenhui Guo, Chao Yue   +8 more
doaj   +1 more source