Results 141 to 150 of about 10,767 (294)

3D Bioprinted Breast Cancer‐Stroma Model with Tailored Migration‐Permissive Bioink Reveals Impact of Adipose‐Derived Stromal Cells on Cancer Cell Migration and Invasion Dynamics

open access: yesAdvanced Healthcare Materials, EarlyView.
A migration‐permissive bioink composed of methacrylated collagen type I and thiolated hyaluronic acid enables 3D bioprinting of breast cancer‐stroma models. Single‐cell tracking reveals that adipose stromal cells enhance tumor cell motility and stromal invasion, accompanied by collagen remodeling, and a shift in tumor cell morphology.
Sabrina Stecher   +19 more
wiley   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He   +9 more
wiley   +1 more source

CoRSEER: The Calculator of Rock Surface Exposure Age and Erosion Rates for Rock Surface Luminescence dating

open access: yes
Abstract. Rock-surface luminescence dating estimates the duration of rock surface exposure and the rate of erosion by analysing changes in luminescence with depth below the surface. The wider use of this method has been slowed by three practical issues: the subjective selection of the deep plateau for profile normalisation, inconsistent modelling ...
Arbaz N. Pathan   +2 more
openaire   +1 more source

POSS‐PEG‐NHS and GSH Cocrosslink DPAV to Prepare Anticalcification Bioprosthetic Scaffold With Enhanced Reendothelization, Anti‐inflammation, and Anti‐ROS

open access: yesAdvanced Healthcare Materials, EarlyView.
POSS‐PEG‐NHS and GSH cocrosslinked DPAV to prepare a multifunctional anticalcification valve substitute. This modification enhances mechanical properties, hemocompatibility, and re‐endothelialization while promoting anti‐inflammatory M2 macrophage infiltration and reducing calcification.
Yuqing Zhang   +10 more
wiley   +1 more source

The deglaciation of the northwest sector of the last British-Irish ice sheet : integrating onshore and offshore data relating to chronology and behaviour [PDF]

open access: yes, 2013
It is now accepted that the last British-Irish Ice Sheet (BIIS) was highly dynamic and drained by numerous fast flowing ice streams. This dynamic nature combined with its maritime location made the BIIS sensitive to the rapid climate change that ...
Small, David
core  

Mixed‐Metal Promotion in a Manganese‐Molybdenum Oxynitride as Catalyst to Integrate C─C and C─N Coupling Reactions for the Direct Synthesis of Acetonitrile from Syngas and Ammonia

open access: yesAdvanced Materials, EarlyView.
Transition metal oxy/carbo‐nitrides show great promise as catalysts for sustainable processes. A Mn‐Mo mixed‐metal oxynitride attains remarkable performance for the direct synthesis of acetonitrile, an important commodity chemical, via sequential C─N and C─C coupling from syngas (C1) and ammonia (N1) feedstocks.
M. Elena Martínez‐Monje   +7 more
wiley   +1 more source

The deglaciation of Kongsfjorden, Svalbard —based on surface exposure dating of glacial erratics and Quaternary geological mapping of Blomstrandhalvøya [PDF]

open access: yes, 2016
Surface exposure dating via 10Be cosmogenic nuclide dating is used, alongside Quaternary geological mapping of landforms and sediments, to reconstruct the course of deglaciation following the Late Weichselian Glacial Maximum in Kongsfjorden, northwest ...
Grant, Oliver Rodney
core  

Beyond Presumptions: Toward Mechanistic Clarity in Metal‐Free Carbon Catalysts for Electrochemical H2O2 Production via Data Science

open access: yesAdvanced Materials, EarlyView.
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu   +3 more
wiley   +1 more source

Surface exposure dating of moraines and alluvial fans in the Southern Central Andes

open access: yes, 2016
The role of tectonics versus climate in controlling the evolution of alluvial fans in discussed controversially. The southern Central Andes and their forelands provide a perfect setting to study climate versus tectonic control of alluvial fans. On the one hand, the region is tectonically active and alluvial fan surfaces are offset by faults. The higher
Terrizzano, Carla Marina   +7 more
openaire   +1 more source

Crystal Growth Engineering for Dendrite‐Free Zinc Metal Plating

open access: yesAdvanced Materials, EarlyView.
This research employed the rare‐earth ion dysprosium (Dy) to modulate aqueous zinc (Zn) metal plating. Integrated multiscale experiments and computational modeling unveiled the preferential adsorption of Dy on specific crystal facets, which activated screw dislocation‐driven Zn growth.
Guifang Zeng   +10 more
wiley   +1 more source

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