Results 171 to 180 of about 548,019 (357)
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Improvement in surface fatigue life of hardened gears by high-intensity shot peening [PDF]
Two groups of carburized, hardened, and ground spur gears that were manufactured from the same heat vacuum induction melted vacuum arc melted (VIM VAR) AISI 9310 steel were endurance tested for surface fatigue.
Townsend, Dennis P.
core +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
The influence of surface plastic deformation (rolling finishing) on the microhardness of the laminate diffusion layer and on the texturization process in it [PDF]
, 2019 O. V. Manko
openalex +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Frontiers in Dentistry, 2016 Objectives: This study aimed to evaluate the effect of different ceramic surface treatments after machining grinding on the biaxial flexural strength (BFS) of machinable dental ceramics with different crystalline phases.
Hossein Bagheri +2 more
doaj
Friction Coefficients on Surface Finish of AlTiN Coated Tools in the Milling of Ti6Al4V
, 2017 Mohammad Akmal +4 more
openalex +1 more source
Innovative Surface Finishing Society of Japan aiming for the 100<sup>th</sup> anniversary
, 2020 Morio Matsunaga
openalex +2 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source