Results 171 to 180 of about 50,696 (309)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The Discussion of Uncertainties in Surface Texture during Design, Manufacture and Measurement
The objective of this paper is to examine different uncertainties between design, manufacture and measurement in surface texture by carrying out a deeply discussion and seeking possible evaluation methods.
Ding, Hao +4 more
core
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Surface finish measurement studies
, 1983 The performance of stylus instruments for measuring the topography of National Transonic Facility (NTF) model surfaces both for monitoring during fabrication and as an absolute measurement of topography was evaluated.
Teague, E. C.
core
Tool Wear and Surface Finish in AISI 304 Stainless Steel Dry Turning with Cermet Inserts. [PDF]
Materials (Basel)Magalhães LC +3 more
europepmc +1 more source
Polydopamine-Lysophosphatidate-Functionalised Titanium: A Novel Hybrid Surface Finish for Bone Regenerative Applications. [PDF]
Molecules, 2020 Baldwin F +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Impact of Cutting Parameters and Tool Type on Surface Finish in MQL Turning of Inconel 625. [PDF]
Materials (Basel)Machno M, Zębala W, Franczyk E.
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Effect of thickness and surface finish on light transmission through zirconia-reinforced lithium silicate and lithium disilicate dental ceramics. [PDF]
Braz Dent JBraga SSL +5 more
europepmc +1 more source