Results 51 to 60 of about 50,696 (309)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Mutual influence of cross hatch angle and superficial roughness of honed surfaces on friction in ring-pack tribo-system [PDF]

open access: yes, 2013
The cylinder bore surface texture, widely produced by the honing technique, is an essential factor for a good engine performance (friction, oil consumption, running-in, wear etc.).
EL MANSORI, Mohamed   +3 more
core   +1 more source

ASSESSMENT OF SURFACE FINISH AND DIMENSIONAL ACCURACY OF TOOLS MANUFACTURED BY METAL CASTING IN RAPID PROTOTYPING SAND MOULDS

open access: yesSouth African Journal of Industrial Engineering, 2012
In this paper, an initial assessment of the quality parameters of the surface finish and dimensional accuracy of tools made by metal casting in rapid prototyping (RP) sand moulds is undertaken.
Nyembwe, K.   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Characterization and Modeling of Surface Roughness and Burr Formation in Slot Milling of Polycarbonate

open access: yesJournal of Manufacturing and Materials Processing, 2020
Thermoplastic materials hold great promise for next-generation engineered and sustainable plastics and composites. However, due to their thermoplastic nature and viscoplastic material response, it is difficult to predict the properties of surfaces ...
David Adeniji   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Elid superfinishing of spherical bearings [PDF]

open access: yes, 2007
Driven by a requirement to extend the lifespan of self-aligning lined spherical bearings, this research investigates the use of Elid (electrolytic in-process dressing) as a method of improving ball surface finish.
Raffles, Mark H.
core  

Nanofinishing of freeform/sculptured surfaces: state-of-the-art

open access: yesManufacturing Review, 2018
Freeform surfaces are being used in a multiplicity of applications in different kinds of industries related to Bio-medical (Bio-implants), micro channels in micro fluidics, automotives, turbine blades, impellers of artificial heart pumps, automobiles etc.
Nagdeve Leeladhar   +2 more
doaj   +1 more source

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