Results 131 to 140 of about 6,390,963 (305)

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

open access: yesAdvanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren   +6 more
wiley   +1 more source

The Spatiotemporal Surface Velocity Variations and Analysis of Amery Ice Shelf, East Antarctica

open access: yes
The surface velocity of the Amery Ice Shelf (AIS) is vital to assessing its stability and mass balance. Previous studies have shown that the AIS basin has a stable multi-year average surface velocity. However, spatiotemporal variations in the surface velocity of the AIS and the underlying physical mechanism remain poorly understood. This study combined
Ma yuan Yuan   +4 more
openaire   +1 more source

A Noninvasive Approach to Study Localized Forces in 3D Epithelia

open access: yesAdvanced Materials, EarlyView.
Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand   +9 more
wiley   +1 more source

Modelling seasonal meltwater forcing of the velocity of land-terminating margins of the Greenland Ice Sheet

open access: yes, 2018
. Surface runoff at the margin of the Greenland Ice Sheet (GrIS) drains to the ice-sheet bed, leading to enhanced summer ice flow. Ice velocities show a pattern of early summer acceleration followed by mid-summer deceleration due to evolution of the ...
Conrad P. Koziol, N. Arnold
semanticscholar   +1 more source

Assessing controls on mass budget and surface velocity variations of glaciers in Western Himalaya

open access: yesScientific Reports, 2018
This study analyses spatially resolved estimates of mass budget and surface velocity of glaciers in the Zanskar Basin of Western Himalaya in the context of varying debris cover, glacier hypsometry and orientation. The regional glacier mass budget for the
Shashank Bhushan   +4 more
semanticscholar   +1 more source

Quantifying subglacial roughness and its link to glacial geomorphology and ice speed [PDF]

open access: yes, 2013
The shape of subglacial bed topography, termed its roughness, is a recognised control on basal ice-flow. Although glaciologists have observed patterns of variations in ice speed over beds with different roughness values, the strength of this relationship
PRESCOTT, PHILIP,WILLIAM
core  

Amphiphilic Non‐Isocyanate Polyurethane Coatings With Tunable Antifouling and Fouling‐Release Performance: A Log‐Ratio Assessment Framework

open access: yesAdvanced Materials Interfaces, EarlyView.
Amphiphilic non‐isocyanate polyurethane (NIPU) coatings containing reactive hydrophobic poly(dimethylsiloxane) (PDMS) and hydrophilic methoxy poly(ethylene glycol) (MPEG) prepolymers for marine antifouling (AF) and fouling‐release (FR) applications were investigated. The coatings were evaluated with a set of representative marine foulants.
Nastaran Shahzadeh   +7 more
wiley   +1 more source

ITS_LIVE global glacier velocity data in near-real time

open access: yesThe Cryosphere
. Glaciers and ice sheets cover some 15 million square kilometers of the Earth's surface, shaping continental landscapes and modifying climate on a global scale.
A. Gardner   +8 more
semanticscholar   +1 more source

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

open access: yesAdvanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang   +7 more
wiley   +1 more source

Direct determination of the air‐sea CO2 gas transfer velocity in Arctic sea ice regions

open access: yes, 2017
The Arctic Ocean is an important sink for atmospheric CO2. The impact of decreasing sea ice extent and expanding marginal ice zones on Arctic air‐sea CO2 exchange depends on the rate of gas transfer in the presence of sea ice.
J. Prytherch   +8 more
semanticscholar   +1 more source

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