Results 131 to 140 of about 1,347,538 (354)

Modeling of multifunctional deformable porous scaffolds for soft tissue engineering [PDF]

open access: yes, 2012
Porous membranes/scaffolds such as guided tissue regeneration (GTR) membranes, cell sheets, tissue matrices or polymeric meshes are being widely used in soft tissue engineering to regenerate damaged, diseased tissue or wound.
Khoda, AKM, Koç, Bahattin
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

How non-conventional machining affects the surface integrity and magnetic properties of non-oriented electrical steel

open access: gold, 2021
Kieran Winter   +5 more
openalex   +1 more source

Loss of solutions in shear banding fluids in shear banding fluids driven by second normal stress differences

open access: yes, 2011
Edge fracture occurs frequently in non-Newtonian fluids. A similar instability has often been reported at the free surface of fluids undergoing shear banding, and leads to expulsion of the sample.
Bascom W. D.   +8 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Grinding EB-PBF based additive manufactured Ti6Al4V: A surface integrity study

open access: gold, 2023
Chandra Sekhar Rakurty   +6 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Influence of Surface Integrity after Turning on the Consecutive Plasma Nitridation and Barkhausen Noise Emission [PDF]

open access: diamond, 2018
Anna Mičietová   +4 more
openalex   +1 more source

Investigation on different composition of powder metallurgy electrode (Cu-W) in high performance edm (HPEDM) on AISI D2 hardened steel [PDF]

open access: yes, 2013
The ideal selection of manufacturing conditions is one of the most important aspects to take into consideration in the majority of manufacturing processes and particularly in processes related to Electrical Discharge Machining (EDM).
Abdul Hamid, Faizul Ezmat
core  

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