Results 41 to 50 of about 412,203 (293)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Investigation of thermodynamic properties in picosecond laser-produced plasmas on silicon

AIP Advances, 2023
The validity of local thermodynamic equilibrium (LTE) in plasma is a long-term concern for laser-induced breakdown spectroscopy applications. In this paper, the spatial and temporal dependence of LTE deviation in picosecond laser-induced plasmas has been
Zelin Liu, Minsun Chen, Hanchang Huang, Shuai Hu, Chuan Guo, Hao Liu, Zhongjie Xu, Guomin Zhao, Weihong Hua, Kai Han   +9 more
doaj   +1 more source

Theory of high harmonic generation in relativistic laser interaction with overdense plasma [PDF]

, 2006
High harmonic generation due to the interaction of a short ultra relativistic laser pulse with overdense plasma is studied analytically and numerically.
A. Pukhov, F. Krausz, J. D. Jackson, L. D. Landau, L. Plaja, N. G. de Bruijn, S. Gordienko, S. V. Bulanov, T. Baeva, Y. I. Salamin   +9 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Enhanced surface acceleration of fast electrons by using sub-wavelength grating targets

, 2010
Surface acceleration of fast electrons in intense laser-plasma interaction is improved by using sub-wavelength grating targets. The fast electron beam emitted along the target surface was enhanced by more than three times relative to that by using planar
Hu, Guang-yue, Huang, Lin-gen, Lei, An-le, Li, Ru-xin, Liu, Jian-sheng, Shen, Bai-fei, Wang, Jing-wei, Wang, Wen-tao, Wang, Xin, Xu, Yi, Xu, Zhi-zhan, Yu, Wei   +11 more
core   +1 more source

Role of surface roughness in hard x-ray emission from femtosecond laser produced copper plasmas [PDF]

, 2002
The hard x-ray emission in the energy range of 30-300 keV from copper plasmas produced by 100 fs, 806 nm laser pulses at intensities in the range of 10$^{15}-10^{16}$ W cm$^{-2}$ is investigated.
A. S. Sandhu, A.G.M. Maaswinkel, C. Wulker, D. Giulietti, D.W. Forslund, F. Brunel, G. Kulcsar, G. R. Kumar, H. Ahn, H. Chen, H. Nakano, H.M. Milchberg, J.C. Kieffer, J.D. Kmetec, J.F. Pelletier, J.J. Thomson, K. Estabrook, K.R. Manes, L. C. Tribedi, M. Murnane, M. Schnurer, M. Schnurer, M.K. Grimes, M.M. Murnane, P. Gibbon, P. P. Rajeev, P. Zhang, Paul Gibbon, R. C. Issac, R. Fedosejevs, R. Sauerbrey, R.A. Cairns, R.J. Faehl, S. Banerjee, S. Banerjee, S. Banerjee, S. Banerjee, S. Bastiani, Tadashi Nishikawa, Tadashi Nishikawa, U. Teubner, V.P. Silin, Y. Zhang   +42 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Laser-Induced Ion Formation and Electron Emission from a Nanostructured Gold Surface at Laser Fluence below the Threshold for Plasma Formation

Nanomaterials, 2023
The laser formation of positive and negative ions on a nanostructured metal surface is observed at laser fluence below the plasma formation threshold.
Andrey Pento, Ilya Kuzmin, Viacheslav Kozlovskiy, Lei Li, Polina Laptinskaya, Yaroslav Simanovsky, Boris Sartakov, Sergey Nikiforov   +7 more
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Laser Induced Damage Studies in Borosilicate Glass Using nanosecond and sub nanosecond pulses

, 2016
The damage mechanism induced by laser pulse of different duration in borosilicate glass widely used for making confinement geometry targets which are important for laser driven shock multiplication and elongation of pressure pulse, is studied.
Chaurasia, S., Munda, D. S., Rastogi, Vinay   +2 more
core   +1 more source