Results 141 to 150 of about 5,907,774 (261)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Evolution of Microstructure and Surface Property of 18CrNiMo7-6 Steel During Vacuum High-Temperature Boriding Process

18CrNiMo7-6 steel is widely used in high-load mechanical components, but its poor surface hardness and corrosion resistance limit its service life. This study performed vacuum solid boriding treatment on 18CrNiMo7-6 steel at 1000 °C for different ...
Hao Li, Yanmin Li, Ke Mao
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Metal Surface Modification on the Basis of Micro-arc Oxidation Technology

Metal surface modification on the basis of Micro-arc Oxidation ...
Urbahs, Aleksandrs, Zujevs, Vladimirs, Savkovs, Konstantins, Rijkuris, Gints   +3 more
core  

Biofunctional Surface Modification of Polymeric Implants for Biomedical Applications. [PDF]

Macromol Rapid Commun
Tripathi R, Reddy MS, Rajput S.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Quantitative evaluation of coloration and functionalization efficiency for surface modification of regenerated cellulose fabrics. [PDF]

Sci Rep
Gaafer RRT, Ameen HA, Abo El Naga HTES, El-Aziz MYA, Eid BM.   +4 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Biopolymer Surface Modification as a Strategy for Conferring "Stealth-like" Characteristics of Xanthohumol-Loaded Liposomes. [PDF]

Polymers (Basel)
Simeonov P, Todorova V, Batsalova T, Dzhambazov B, Ivanova S, Katsarov P.   +5 more
europepmc   +1 more source