Results 171 to 180 of about 2,011,030 (309)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Impact of Laser Surface Modification on Zirconia Implants: A Systematic Review of In Vitro Evidence. [PDF]

Cureus
Bhosale S, Gangurde A, Chauhan M, Jaiswal N, Harimkar RL, Shaikh S.   +5 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Numerical and Experimental Study of Laser Surface Modification Using a High-Power Fiber CW Laser. [PDF]

Materials (Basel)
Kaselouris E, Gosta A, Kamposos E, Rouchotas D, Vernardos G, Papadaki H, Skoulakis A, Orphanos Y, Bakarezos M, Fitilis I, Papadogiannis NA, Tatarakis M, Dimitriou V.   +12 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Analysis of meshing performance of face gear with full tooth surface modification

Jixie chuandong
ObjectiveTo investigate the influence of a modified tooth surface on the meshing performance of face gear pair, a full tooth surface modification method for face gear was proposed to optimize their meshing performance.MethodsFirstly, the standard tooth ...
HE Kun, CHEN Yongquan, DU Yanbin, LI Ronghao   +3 more
doaj  

Magnetoplasmonic Nanostructures from Magnetite with Noble Metal Surface Modification and Their Antimicrobial Activity. [PDF]

Int J Mol Sci
Ardeleanu H, Ardeleanu MC, Dunca S, Grigoras M, Ababei G, Pricop D, Ursu L, Bulai G, Timpu D, Lupu N, Ciobica A, Racuciu M, Creanga D.   +12 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Improved adhesion and function of Pediococcus pentosaceus Li05 for acute colitis through surface modification. [PDF]

NPJ Sci Food
Han S, Wang K, Su K, Dong X, Huang Y, Lu Y, Zhang S, Qiu B, Li Y, Xiao H, McClements D, Berglund B, Yao M, Li L.   +13 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source