ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou +9 more
wiley +1 more source
Surface Plasmon Resonance as a Tool in Antiviral Drug Discovery Research. [PDF]
Wegrzyn KE, Matsoukas JM.
europepmc +1 more source
A deep comprehension of biomolecular phenomena at interfaces is significant with their fundamental and practical importance. Our experimental and theoretical investigations reveal that specific amino acids (glutamic acid and aspartic acid) exhibit an orientational coupling with liquid crystals, which can recognize and optically report the interfacial ...
Yena Choi +10 more
wiley +1 more source
Surface Plasmon Resonance Analysis for Evaluating ASO Targeting Structured RNA. [PDF]
Shinozaki T +5 more
europepmc +1 more source
Light‐Harvesting Photothermal Hotspots Enabled by NIR Scattering‐Absorption Coupling
By coupling the broadband scattering of nanodiamonds with the plasmonic absorption of gold nanostars, this work proposes a novel strategy for the active modulation of photon transport. This strategy creates localized photothermal hotspots in turbid media and achieves a supra‐additive heating efficiency, thereby providing a universal platform for low ...
Zebin Wu +17 more
wiley +1 more source
Quantitative determination of in-plane optical anisotropy by surface plasmon resonance holographic microscopy. [PDF]
Zhang J +8 more
europepmc +1 more source
Energy‐Resolved Femtosecond Dynamics of Plasmon‐Induced Hole Injection at Au/GaN Heterointerfaces
We reveal the spectral signature of ultrafast nonthermal hot‐hole transfer at plasmonic heterointerfaces, which reshapes hot‐carrier relaxation dynamics and significantly enhances hydrogen evolution, providing a mechanistic basis for optimizing hot‐carrier utilization in photocatalysis.
Yuying Gao +8 more
wiley +1 more source
Surface plasmon resonance biosensors: Advancements, applications, and future directions in molecular detection. [PDF]
El Biyari N.
europepmc +1 more source
Abstract The accurate detection of glucose in wound exudate is critically important for monitoring chronic wound healing. While photoelectrochemical (PEC) sensors are widely used, they often suffer from material degradation caused by redox reactions during operation. Herein, we introduce a dark‐field microscopy (DFM) setup integrated with a PEC system,
Zihao Zhang +7 more
wiley +1 more source
Development and Applications of Electrochemical Surface Plasmon Resonance (EC-SPR)-Based Sensors: A Review. [PDF]
Vasconcelos JS +3 more
europepmc +1 more source

