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Surface Plasmon Resonance (SPR) Biosensors in Pharmaceutical Analysis

Critical Reviews in Analytical Chemistry, 2015
This review aims to highlight the applications of one of the most prominent optical biosensor technologies, surface plasmon resonance (SPR), in the drug discovery process and quality analysis of pharmaceutical compounds and their particularities. SPR assay formats and experimental issues are used for pharmacokinetic drug profiling, ADMET studies, high ...
Camelia Bala   +2 more
exaly   +4 more sources

Nano Sensing and Energy Conversion Using Surface Plasmon Resonance (SPR) [PDF]

open access: yesMaterials, 2015
Nanophotonic technique has been attracting much attention in applications of nano-bio-chemical sensing and energy conversion of solar energy harvesting and enhanced energy transfer. One approach for nano-bio-chemical sensing is surface plasmon resonance (SPR) imaging, which can detect the material properties, such as density, ion concentration ...
Iltai Kim
exaly   +4 more sources

Surface Plasmon Resonance (SPR) biosensor for detection of mycotoxins: A review

Journal of Immunological Methods, 2022
Mycotoxin is one of the most important natural pollutants, which poses a global threat to food safety. However, the pollution of mold in food production is inevitable. The detection technology of mycotoxins in food production is an important means to prevent the damage of mycotoxins, so rapid detection and screening to avoid pollution diffusion is ...
Xiuxia, Wei   +6 more
openaire   +2 more sources

Variable wavelength surface plasmon resonance (SPR) in biosensing

Biosystems, 2009
In this study, we fabricated a novel variable wavelength surface plasmon resonance (SPR) sensor, which detects resonance conditions such as a maximum attenuation wavelength, measuring change of microscopic refractive index. Such a change was measured to detect a salmonella antigen-antibody reaction and a penicillinase-penicillin reaction.
Nyeon-Sik Eum   +6 more
openaire   +2 more sources

Rapid method for detection of Salmonella in milk by surface plasmon resonance (SPR)

Biosensors and Bioelectronics, 2007
The Plasmonic surface plasmon resonance (SPR) device was used to develop a rapid, simple and specific immunoassay for detection of Salmonella in milk. Rapid detection of Salmonella contamination is a major challenge for the food industry. Salmonella contamination is well known in all foods including pasteurised milk.
Peter Kampfer   +2 more
exaly   +3 more sources

Application of chromogenic reagents in surface plasmon resonance (SPR)

Biosensors and Bioelectronics, 2007
In this paper, a new simple approach for sensitivity optimization in surface plasmon resonance (SPR) chemosensors based on colorimetric ligands is presented. A new design of SPR sensor with tunable analytical wavelength (lambda(SPR)) was constructed for this purpose, to perform studies on the ligand absorbance spectra related sensitivity enhancement ...
Jan, Mavri   +2 more
openaire   +2 more sources

Gold-nanoshells as surface plasmon resonance (SPR)

SPIE Proceedings, 2015
Coreshell plasmonic nanoparticles (CS) are a class of nanoparticles that exhibit optical absorption in the near IR regime and have potential biomedical applications in imaging, therapy and sensing. We present our preliminary investigation on the applications of CS as a surface plasmon based sensor to study the functional properties of human blood.
K. Sathiyamoorthy, Michael C. Kolios
openaire   +1 more source

Surface Plasmon Resonance (SPR) Sensors

2006
4 Main Performance Characteristics of SPR Sensors . . . . . . . . . . . . . . 49 4.1 Sensitivity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 4.1.1 Sensitivity of SPR Sensors with Angular Modulation . . . . . . . . . . . . . 52 4.1.2 Sensitivity of SPR Sensors with Wavelength Modulation . . . . . . . . . . .
Jiří Homola, Marek Piliarik
openaire   +1 more source

Surface plasmon resonance (SPR) as a rapid tool for serotyping of Salmonella

Biosensors and Bioelectronics, 2010
An SPR-based sandwich immunoassay for serotyping of Salmonella is demonstrated. The Salmonella are captured on an SPR chip using polyclonal capture antibody. SPR sensorgrams are obtained for the immunoreactions of the somatic (O) and flagellar (H) surface antigens, of the captured bacteria, to their respective antibodies.
Saikat Datta, Mazumdar   +3 more
openaire   +2 more sources

A rapid method for detection of PrP by surface plasmon resonance (SPR)

Archives of Virology, 2009
Surface plasmon resonance was used to develop a rapid, label-free and sensitive immunoassay for detection of Prion protein (PrP). Anti-PrP monoclonal antibodies immobilized on the biosensor surface were allowed to bind various concentrations of cellular prion protein (PrP(C)), followed by a pulse with additional soluble anti-PrP polyclonal antibodies ...
Wan, Jiayu   +8 more
openaire   +2 more sources

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