The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Tropical convective outflow and near surface equivalent potential temperatures [PDF]
Ian Folkins +2 more
openalex +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
We demonstrate that single-pass Kelvin force microscopy (KFM) and capacitance gradient (dC/dZ) measurements with force gradient detection of tip–sample electrostatic interactions can be performed in the intermittent contact regime in different ...
Sergei Magonov, John Alexander
doaj +1 more source
A Survey of the Ionization Energies of the DNA Nitrogenous Bases via DFT-Based Calculations of their Potential Energy Surfaces [PDF]
Hwoi Chan Kwon +3 more
openalex +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Negative Voltage Electrospinning for the Production of Highly Efficient PVDF Filters
In recent years, the demand for filter media has increased dramatically, driven by the need to manufacture personal protective equipment and for various applications in the industrial and civil sectors. Nanofiber‐based membranes are proposed as potential
Carlo Gotti +8 more
doaj +1 more source
Long-Range Complex in the HC$$_{3}$$N + CN Potential Energy Surface: Ab Initio Calculations and Intermolecular Potential [PDF]
Emília Valença Ferreira de Aragão +5 more
openalex +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
Inverse problem in Lagrangian dynamics: special solutions for potentials possessing families of regular orbits on a given surface [PDF]
Thomas Kotoulas
openalex +1 more source

