Results 161 to 170 of about 27,708,048 (352)

Multiyear in-situ L-band microwave radiometry of land surface processes on the Tibetan Plateau. [PDF]

Sci Data, 2020
Su Z, Wen J, Zeng Y, Zhao H, Lv S, van der Velde R, Zheng D, Wang X, Wang Z, Schwank M, Kerr Y, Yueh S, Colliander A, Qian H, Drusch M, Mecklenburg S.   +15 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Surface deformation resulting from subduction and slab detachment

, 2000
Convergence of lithospheric plates is accommodated at active margins by one plate moving beneath the other into the Earth's mantle. Changes in this subduction process may cause variations in the topography of the Earth's surface near a convergent plate
Lithospheric dynamics and fundamental aspects of tectonic processes, Tectonophysics, IVAU: Instituut voor Aardwetenschappen Utrecht, Dep Aardwetenschappen, Buiter, S.J.H.   +4 more
core  

Interrill soil erosion processes and their interaction on low slopes

, 2007
Soil erosion by water is mostly the result of rainfall-driven and runoff-driven processes taking place simultaneously during a storm event. However, the effect of interaction between these two erosion processes has received limited attention.
Asadi, H, Rose, CW, Gnadiri, H, Rouhipour, H   +3 more
core   +1 more source

Geospatial green ammonia co-firing in China’s coal power fleets to avoid CO2 emissions lock-in

Nature Communications
China’s 600 gigawatts (GW) of post-2010 coal power capacity locks in over 2 gigatons (Gt) of annual CO₂ emissions. Green ammonia co-firing offers a viable decarbonization pathway, yet spatial mismatch between ammonia production hubs and coal power plants
Huihuang Wu, Xiurong Hu, Xian Wang, Yuhan Zhou, Junfeng Liu, Yang Ren, Boyang Wu, Wendong Ge, Ying Liu, Shu Tao   +9 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The geomorphology of coarse clastic surfaces in arid environments [PDF]

, 2002
This study explores the linkages between slope form and slope process in arid environments. In doing so, questions of the development of slopes in arid environments are examined.
Rosser, Nicholas John
core  

Process, Causes, and Loss Assessment of the Extreme Wind-Dust Compound Disaster in China in April 2025

International Journal of Disaster Risk Science
From 10 to 15 April 2025, China experienced a rare persistent extreme wind-dust compound disaster that swept from north to south. Based on observational data, historical disaster records, and situations of various exposed elements, this study analyzed ...
Gangfeng Zhang, Yiwen Wang, Lianyou Liu, Yaoyao Ma, Ziqi Lin, Wenxuan Li, Tong Zhang, Siqi Liu, Xiaoxiao Zhang, Shuo Wang, Zhe Liu, Jinpeng Hu, Peijun Shi   +12 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The effects of machining process variables and tooling characterisation on the surface generation: modelling, simulation and application promise

, 2005
The paper presents a novel approach for modelling and simulation of the surface generation in the machining process. The approach, by integrating dynamic cutting force model, regenerative vibration model, machining system response model and tool profile ...
Cheng, K, Luo, X, Ward, R
core   +1 more source