NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Impact of Treatment Methods on the Surface Properties of the Mg-Containing Zeolite Y. [PDF]
Biessikirski A +6 more
europepmc +1 more source
Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco +18 more
wiley +1 more source
Application of Argon Ion Implantation to Improve the Surface Properties of Materials Based on PLA and Lignocellulosic Particles. [PDF]
Betlej I +4 more
europepmc +1 more source
Heat of Immersion and the Surface Properties of Zeolite and Magnesia
Тошио Сакурай +2 more
openalex +2 more sources
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Complex interplay of surface properties in modulating antibacterial activity of Ti50Zr alloys. [PDF]
Constantinescu A +3 more
europepmc +1 more source
Knee crepitus and osteoarthritis features in young adults following traumatic knee injury
Objective This study explored the association between knee crepitus and the presence, and worsening, of structural osteoarthritis features and self‐reported outcomes in young adults following traumatic knee injury. Methods One‐year following anterior cruciate ligament reconstruction (ACLR), 112 participants (41 female participants; median age 28 years)
Jamon L Couch +8 more
wiley +1 more source
Improvement of Surface Properties of Carbon Steel Through Electrospark Coatings from Multicomponent Hard Alloys. [PDF]
Penyashki T, Kostadinov G, Kandeva M.
europepmc +1 more source

