Results 51 to 60 of about 482,940 (315)

Intensification of sediment loss on land surfaces in calabar river catchment, cross river state, Nigeria. [PDF]

Riscuri şi Catastrofe, 2020
Soil loss is a direct consequence of soil erosion which is a function of rainfall amount, intensity and duration as well as surface configuration (relief/slope), nature of surface materials and vegetation.
ABUA, M.A., ABALI, T.P, IGELLE, E. I
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Assessing Multiple Risks in Regulating Reservoirs: Perspectives on Heavy Metal Contamination

Toxics
As the terminal reservoir of the South-to-North Water Diversion’s Eastern Route, Dongping Lake is critical for safeguarding the northern water supply. Analysis of 33 water–sediment sites revealed the following. (1) Waterborne heavy metals (HMs) below WHO
Hui Zhou, Zhiping Li, Anming Wang, Jiawei Zhu, Zongyuan Han, Yalin Zhang, Dongdong Chen   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Changes and Influencing Factors of Carbon Content in Surface Sediments of Different Sedimentary Environments Along the Jiangsu Coast, China

Diversity
Coastal areas are essential for global ‘blue carbon’ burial, significantly impacting the global carbon cycle. To better understand the carbon burial capacity, impact factors, and response mechanisms of surface sediments in different coastline regions ...
Linlu Xu, Hui Ye, Jianing Yin, Qiang Shu, Yuxin Fan   +4 more
doaj   +1 more source

A novel subsurface sediment plate method for quantifying sediment accumulation and erosion in seagrass meadows

Frontiers in Marine Science, 2023
Sediment dynamics in seagrass meadows are key determinants of carbon sequestration and storage, surface elevation, and resilience and recovery from disturbance. However, current methods for measuring sediment accumulation are limited.
Carolyn J. Ewers Lewis, Karen J. McGlathery   +1 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Sediment reworking by marine benthic species from the Gullmar Fjord (Western Sweden): Importance of faunal biovolume [PDF]

, 2007
In order to compare and quantify sediment reworking activities by different species/functional groups of macrofauna, a laboratory experiment was carried out with species from the Gullmarsfjord (Western Sweden).
Desrosiers, Gaston, François-Carcaillet, Frédérique, Gilbert, Franck, Grossi, Vincent, Gérino, Magali, Hulth, Stefan, Michaud, Emma, Poggiale, Jean-Christophe, Rosenberg, Rutger, Stora, Georges   +9 more
core   +6 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source