Results 71 to 80 of about 482,940 (315)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Application and evaluation of sediment fingerprinting techniques in the Manawatu River catchment, New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Geography at Massey University, Palmerston North, New Zealand [PDF]

, 2016
Suspended sediment is an important component of the fluvial environment, contributing not only to the physical form, but also the chemical and ecological character of river channels and adjacent floodplains.
Vale, Simon
core  

Warming the early Earth - CO2 reconsidered

, 2008
Despite a fainter Sun, the surface of the early Earth was mostly ice-free. Proposed solutions to this so-called "faint young Sun problem" have usually involved higher amounts of greenhouse gases than present in the modern-day atmosphere.
Barbara Stracke, Beate Patzer, Brown, Caldeira, Cess, Colaprete, Franz Schreier, Goody, Goody, Gough, Grenfell, Grenfell, Heike Rauer, Hessler, Ingersoll, J. Lee Grenfell, Jenkins, Kasting, Kasting, Kasting, Kasting, Kasting, Kasting, Kasting, Knauth, Lacis, Manabe, Minton, Mischna, Mlawer, Mojzsis, Pascal Hedelt, Pavlov, Pavlov, Pavlov, Philip von Paris, Robert, Rosing, Rothman, Rye, Sagan, Sagan, Schreier, Segura, Segura, Shaviv, Shields, Sleep, Thomas Trautmann, Toon, Toth, Towe, Vardavas, Vardavas, West, Wiscombe   +55 more
core   +1 more source

Lateral Marsh Edge Erosion as a Source of Sediments for Vertical Marsh Accretion [PDF]

, 2018
With sea level rise accelerating and sediment inputs to the coast declining worldwide, there is concern that tidal wetlands will drown. To better understand this concern, sources of sediment contributing to marsh elevation gain were computed for Plum ...
Barbier, Bauer, Blum, Blum, Cahoon, Cavatorta, Claessens, Cook, Costanza, Day, Day, Dhillon, Donnelly, Donnelly, Engelhart, Eyre, Fagherazzi, Fagherazzi, Foley, Forbrich, French, Ganju, Ganju, Geyer, Gittman, Gosselink, Hayden, Hein, Hobbs, Hopkinson, Hughes, Kirwan, Kirwan, Kirwan, Koch, Lane, Leonardi, Leonardi, Leonardi, Levin, Magirl, Marcus, Mariotti, Mariotti, Mariotti, Mattheus, McGeehin, McKee, Meade, Meade, Megonigal, Millette, Milliman, Mineau, Morris, Morris, Morris, Morris, Morris, Mudd, Pasternack, Pavich, Priestas, Rahmstorf, Raymond, Redfield, Redfield, Redfield, Reed, Rovere, Schmidt, Schwimmer, Sholkovitz, Stuiver, Swales, Syvitski, Townsend, Trimble, Vallino, Vallino, Walsh, Warrick, Warrick, Watson, Weston, Wilson, Wollheim, Wollheim, Worm, Yarbro, Zhao   +90 more
core   +3 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Sedimentological survey by the icebreaker Shirase during JARE-61

Antarctic Record
The first systematic sediment survey by the icebreaker Shirase (AGB-5003) was conducted during the 61st Japanese Antarctic Research Expedition (JARE-61).
Takuya Itaki, Yuki Tokuda, Takeshige Ishiwa, Satoshi Sasaki, Yusuke Suganuma, Shigeru Aoki   +5 more
doaj   +1 more source

Composition and Distribution of Microeukaryotic Communities in the Surface Sediments of Five Geographic Regions of Bohai Sea Based on 18S rDNA Amplicon Sequencing

Journal of Marine Science and Engineering
The Bohai Sea is a semi-enclosed shallow water that is influenced by both natural and anthropogenic stressors. However, the microeukaryotic communities and environmental factors that affect them in different regions remain largely unclear.
Wenquan Zhang, Huameng Ge, Chengbing Song, Chengcheng Li, Shenghao Liu   +4 more
doaj   +1 more source

Faunal response to benthic and hyporheic sedimentation varies with direction of vertical hydrological exchange [PDF]

, 2014
1. Sedimentation and clogging of benthic and hyporheic zone substrates is increasingly being recognised as one of the greatest threats to the ecological integrity of riverine ecosystems globally. This ex-situ study examined the influence of sedimentation
Bo, Boano, Boulton, Boulton, Boulton, Brunke, Brunke, Bruno, Collins, Davy-Bowker, Descloux, Descloux, Descloux, Dole-Oliver, Dunbar, Evans, Extence, Fowler, Franken, Gayraud, Gledhill, Greig, Huettel, IBM Corp, Izagirre, Jones, Jones, Joyce, Kemp, Krause, Larned, Larson, MacNeil, MacNeil, Malcolm, Maridet, Navel, Olsen, Pacioglu, Packman, Packman, Pepin, Plenet, Ren, Richards, Robertson, Ryan, Sarriquet, Simpson, Studinski, Stump, Taylor, Walters, Wang, Weigelhofer, Wood, Wood, Xu, Zweig   +58 more
core   +2 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source