Results 71 to 80 of about 1,113,527 (283)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Selection and in vitro Probiotic Properties of Bifidobacterium longum subsp. longum with Anti-diabetic Activity from the Intestinal Tract of Chinese Tajik Children [PDF]

Shipin Kexue
Probiotics have been proven to play a positive role in the prevention and treatment of diabetes. The gut microbiota of different populations harbors an extremely rich diversity of species and strains.
LI Si, AN Meiling, LI Longlong, ZHANG Ruirui, SUN Hailong, NI Yongqing
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Unique footprint in the scl1.3 locus affects adhesion and biofilm formation of the invasive M3-type group A Streptococcus

Frontiers in Cellular and Infection Microbiology, 2016
The streptococcal collagen-like proteins 1 and 2 (Scl1 and Scl2) are major surface adhesins that are ubiquitous among group A Streptococcus (GAS). Invasive M3-type strains, however, have evolved two unique conserved features in the scl1 locus: (i) an ...
Beth Alexandra Bachert, Soo Jeon Choi, P Rocco LaSala, Tiffany I Harper, Dudley H McNitt, Dylan T Boehm, Clayton C Caswell, Pawel Ciborowski, Douglas R Keene, Anthony R Flores, Anthony R Flores, James M Musser, Flavia Squeglia, Daniela Marasco, Rita Berisio, Slawomir Lukomski   +15 more
doaj   +1 more source

Biofilm formation and potential virulence factors of Salmonella strains isolated from ready-to-eat shrimps. [PDF]

PLoS ONE, 2018
Salmonella species is an important foodborne pathogen with the non-typhoidal serovars such as Enteritidis and Typhimurium as the most predominant strains.
Abeni Beshiru, Isoken H Igbinosa, Etinosa O Igbinosa   +2 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Screening and identification of bacterial cellulose-producing strains from waste tobacco leaves and optimization of mixed-strains fermentation process [PDF]

Zhongguo niangzao
The bacterial cellulose-producing strains were isolated and screened from waste tobacco leaves, and the strains were identified by morphologic observation, physiological and biochemical tests and molecular biological identification.
HUANG Lei, LI Yuanyuan, HE Aimin, CHEN Weihua, WANG Xiaoru, CUI Bing, LAI Miao, ZHAO Mingqin
doaj   +1 more source

Mechanical Characterization of Fourth Generation Composite Humerus [PDF]

, 2011
Mechanical data on upper extremity surrogate bones, supporting use as biomechanical tools, is limited. The objective of this study was to characterize the structural behaviour of the fourth-generation composite humerus under simulated physiologic bending,
Albert, Carolyne, Grover, Prateek, Harris, Gerald F, Wang, Mei   +3 more
core   +1 more source

Role of early viral surface antigens in cellular immune response to vaccinia virus [PDF]

, 1976
Infection of mice with the vaccinia virus strain WR, Elstree or DIs, a conditional lethal mutant of vaccinia virus, resulted in the generation of vaccinia virus-specific sensitized cytolytic T lymphocytes (CTL).
Ertl, H., Koszinowski, Ulrich H.
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source