Results 121 to 130 of about 1,833,148 (268)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Surface Structure of Polar Silver Iodide (0001) in Various Liquids: No Indication for a Surface Reconstruction. [PDF]

Chemphyschem
Dreier KN, Latus A, Bechstein R, Kühnle A.   +3 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Electrolyte concentration modulates the surface structure evolution of Au(111) cathodes. [PDF]

Chem Sci
Feng Y, Wang YQ, Fu J, Wang ZC, Wang D, Wan LJ.   +5 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Research on the Anti-Erosion Mechanism of the Shell Surface Structure Based on Numerical Simulation. [PDF]

Biomimetics (Basel)
Wei Z, Zhang C, Liu X, Shen C, Gao M, Li J, Wu Z, Zhu M.   +7 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Surface structure of water from soft X-ray second harmonic generation. [PDF]

Nat Commun
Hoffman DJ, Devlin SW, Garratt D, Jamnuch S, Spies JA, Nebgen BR, Schacher D, Do A, Bernal F, Riffe EJ, Kunnus K, Hampton CY, Duris J, Cesar D, Sudar N, Dakovski GL, Drisdell WS, Lawler KV, Marinelli A, Zuerch MW, Saykally RJ, Schwartz CP, Pascal TA, Koralek JD.   +23 more
europepmc   +1 more source

Elucidation of lipid nanoparticle surface structure in mRNA vaccines. [PDF]

Sci Rep, 2023
Wang MM, Wappelhorst CN, Jensen EL, Chi YT, Rouse JC, Zou Q.   +5 more
europepmc   +1 more source