Results 101 to 110 of about 1,919,199 (295)

V.M. Miklyukov: from dimension 8 to nonassociative algebras

, 2019
In this short survey we give a background and explain some recent developments in algebraic minimal cones and nonassociative algebras. A good deal of this paper is recollections of my collaboration with my teacher, PhD supervisor and a colleague ...
Tkachev, Vladimir G.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Multi-Ecohydrological Interactions Between Groundwater and Vegetation of Groundwater-Dependent Ecosystems in Semi-Arid Regions: A Case Study in the Hailiutu River Basin

Land
The Hailiutu River Basin in northern China represents a semi-arid area where groundwater-dependent ecosystems (GDEs) play a critical role in maintaining regional vegetation structure and ecological stability.
Lei Zeng, Li Xu, Boying Song, Ping Wang, Gang Qiao, Tianye Wang, Hu Wang, Xuekai Jing   +7 more
doaj   +1 more source

Hyperkahler manifolds and nonabelian Hodge theory of (irregular) curves [PDF]

, 2012
Short survey based on talk given at the Institut Henri Poincare January 17th 2012, during program on surface groups. The aim was to describe some background results before describing in detail (in subsequent talks) the results of [Boa11c] related to wild
Boalch, Philip
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Technical note: A low-cost approach to monitoring relative streamflow dynamics in small headwater streams using time lapse imagery and a deep learning model [PDF]

Hydrology and Earth System Sciences
Despite their ubiquity and importance as freshwater habitat, small headwater streams are under-monitored by existing stream gage networks. To address this gap, we describe a low-cost, non-contact, and low-effort method that enables organizations to ...
P. J. Goodling, J. H. Fair, A. Gupta, J. D. Walker, T. Dubreuil, M. Hayden, B. H. Letcher   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Stressor-driven changes in freshwater biological indicators inform spatial management strategies using expert knowledge, observational data, and hierarchical models

Ecological Indicators
Stream ecosystems face continuous pressures from multiple anthropogenic stressors that reshape biological communities and impact ecosystem health and services.
Sean C. Emmons, Matthew J. Cashman, Rosemary M. Fanelli, Greg J. Pond, Gregory B. Noe, Taylor E. Woods, Kelly O. Maloney   +6 more
doaj   +1 more source

A New Evapotranspiration Model Accounting for Advection and Its Validation during SMEX02

Advances in Meteorology, 2013
Based on the crop water stress index (CWSI) concept, a new model was proposed to account for advection to estimate evapotranspiration. Both local scale evaluation with sites observations and regional scale evaluation with a remote dataset from Landsat 7 ...
Yongmin Yang, Hongbo Su, Renhua Zhang, Jianjun Wu, Jianwei Qi   +4 more
doaj   +1 more source