Results 41 to 50 of about 267,622 (264)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Eolian chronology reveals causal links between tectonics, climate, and erg generation
Nature Communications, 2022 Modeling cosmogenic nuclides concentrations from Kalahari Desert Sand reveals the time of sand introduction into the landscape. This coincides with morphotectonic and climatic changes that could have triggered sand production and its impact on the ...
Shlomy Vainer +5 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Przegląd ArcheologicznyThe current state of knowledge about medieval strongholds in the Świder basin has been verified in the course of research on the settlement of the south-eastern frontier of Mazovia.
Katarzyna Skrzyńska
doaj +1 more source
Archaeological Survey in the Surroundings of Kayrit (South Uzbekistan), Preliminary Report for Season 2015 [PDF]
Studia Hercynia, 2016 This text represents an overview of the results of the extensive surface survey, conducted in the hinterland of the site of Burgut Kurgan, south Uzbekistan, during its excavations in 2015.
Ladislav Stančo
doaj
People and Nature, 2023 Facing the dual threats of climate and socioeconomic changes, how Tibet can seize the opportunity for ecological restoration to enhance environmental quality while improving the relationship between humans and nature is of great significance for regional
Yijia Wang +6 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Archaeological Survey in the eastern Kugitang Piedmonts (South Uzbekistan), Preliminary Report for Seasons 2016 and 2017 [PDF]
Studia Hercynia, 2017 This brief report presents a preliminary overview of the results and data gained during the extensive archaeological surface survey conducted in the eastern foothills of the Kugitang Mountains, especially in the northern Pashkhurt basin in the late ...
Ladislav Stančo +5 more
doaj
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Preliminary Report for the Archaeological Survey in the Baysun District (South Uzbekistan), Season 2017 [PDF]
Studia Hercynia, 2018 This report represents an overview of the archaeological data that were acquired by the extensive archae‑ ological surface survey conducted by the Czech‑Uzbek team in the Baysun Mountains, south Uzbekistan, especially on the ridges of Sarymas, Susiztag ...
Ladislav Stančo +7 more
doaj