Results 81 to 90 of about 5,157,090 (300)

The Topology of Branching Universes [PDF]

open access: yes, 2005
The purpose of this paper is to survey the possible topologies of branching space-times, and, in particular, to refute the popular notion in the literature that a branching space-time requires a non-Hausdorff ...
McCabe, Gordon, Gordon Mccabe
core  

Innovative Strategy for Constructing Soft Topology

open access: yes, 2023
To address the complexity of daily problems, soft set theory has emerged as a valuable tool, providing innovative mathematical techniques to manage vast amounts of data and ambiguity.
Ahmad M. Alghamdi, Amlak I. Alajlan
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Topology Noise Removal for Curve and Surface Evolution

open access: yes, 2010
In cortex surface segmentation, the extracted surface is required to have a particular topology, namely, a two-sphere. We present a new method for removing topology noise of a curve or surface within the level set framework, and thus produce a cortical ...
Chao Chen   +3 more
core   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

open access: yesFEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi   +6 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad   +22 more
wiley   +1 more source

A compactness preserving topology for products sets [PDF]

open access: yes, 1975
The purpose of this thesis is to investigate the properties of certain topologies for a countable product of lattice isomorphic factor spaces. The idea of using lattice isomorphisms between factors to define a topology on a product space is due to ...
Howe, Thomas Lavern   +1 more
core  

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai   +13 more
wiley   +1 more source

Chiral adiabatic transmission protected by Fermi surface topology

open access: yesSciPost Physics
We demonstrate that Andreev modes that propagate along a transparent Josephson junction have a perfect transmission at the point where three junctions meet.
Isidora Araya Day, Kostas Vilkelis, Antonio L. R. Manesco, Ahmet Mert Bozkurt, Valla Fatemi, Anton R. Akhmerov
doaj   +1 more source

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