Results 81 to 90 of about 15,204,033 (285)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Aquatic life status, year 2000

, 2000
Title from web page.; Harvested from the web on 2/6 ...
Ohio EPA.Division of Surface Water.
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Water Quality Models and their Use in Monitoring the Quality of Surface Water Bodies

International Journal for Research in Applied Science and Engineering Technology, 2021
Water quality has been considered as one of the major challenges in water resource management. The main reason of degradation of water quality over the years is anthropogenic activities. Also, the monitoring of surface water bodies is a tedious as well as expensive process.
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

EVALUATION OF SURFACE WATER QUALITY IN PORSUK STREAM

ANADOLU UNIVERSITY JOURNAL OF SCIENCE AND TECHNOLOGY –C Life Sciences and Biotechnology, 2016
Porsuk Cayi, Kutahya ve Eskisehir il sinirlarindan gecerek Turkiye’nin onemli su potansiyellerinden biri olan Sakarya Nehri’ni besleyen onemli bir akarsudur. Ozellikle, Eskisehir iline kadar olan kisminin kullanma suyu olarak degerlendirilmesi nedeni ile Porsuk Cayi’nin su kalitesinin belirlenmesi bolgede bulunan ekosistemlerin sagligi acisindan buyuk ...
KÖSE, Esengül, ÇİÇEK, Arzu, UYSAL, Kazım, TOKATLI, Cem, ARSLAN, Naime, EMİROĞLU, Özgür   +5 more
openaire   +5 more sources

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Conjunctive use of surface water and groundwater with quality considerations [PDF]

Deterministic models of conjunctive surface and groundwater management aren’t much more complicated than typical groundwater-only management models under simple assumptions.
Catarina Roseta Palma
core  

Trend analysis of River water quality: A case study on Gadar-Chai River [PDF]

Journal of Applied Research in Water and Wastewater
Water quality in rivers is a critical concern in hydrology. This study examines the Gadar-Chai River, situated within Iran's Urmia Lake basin, utilizing data from four selected hydrometric stations: Oshnavieh, Polebahramlu, Bighaleh, and Naghadeh.
Neda Jafari, Yagob Dinpashoh, Ahmad Fakheri-Fard   +2 more
doaj   +1 more source