Results 101 to 110 of about 542,344 (303)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Wind Speed‐Up in Wind Farm Wakes Quantified From Satellite SAR and Mesoscale Modeling

Wind Energy
Satellite synthetic aperture radar (SAR) provides ocean surface wind fields at 10 m above sea level. The objective is to investigate the capability of SAR satellite StriX observations for mapping offshore wind farm wakes.
Charlotte Bay Hasager, James Imber, Jana Fischereit, Aito Fujita, Krystallia Dimitriadou, Merete Badger   +5 more
doaj   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Surface Wind Speed Changes and Their Potential Impact on Wind Energy Resources Across China During 1961-2021. [PDF]

Geohealth, 2023
Zhao X, Wu Y, Su J, Gou J.
europepmc   +1 more source

Excitation of interfacial waves via near---resonant surface---interfacial wave interactions

, 2019
We consider interactions between surface and interfacial waves in the two layer system. Our approach is based on the Hamiltonian structure of the equations of motion, and includes the general procedure for diagonalization of the quadratic part of the ...
Lvov, Yuri V, Zaleski, Joseph, Zaleski, Philip   +2 more
core  

Improved near-surface wind speed characterization using damage patterns

Journal of Wind Engineering and Industrial Aerodynamics, 2018
Abstract Tornadoes have caused significant damage and casualties in the past decades. These losses have spurred efforts toward tornado-based design, which requires an accurate estimate of the near-surface tornadic wind speeds. Due to the difficulty of obtaining in-situ measurements and various issues regarding Enhance Fujita (EF) scale, a promising ...
Daniel M. Rhee, Franklin T. Lombardo
openaire   +2 more sources

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Evaluation of global terrestrial near-surface wind speed simulated by CMIP6 models and their future projections. [PDF]

Ann N Y Acad Sci, 2022
Shen C, Zha J, Li Z, Azorin-Molina C, Deng K, Minola L, Chen D.   +6 more
europepmc   +1 more source

Numerical simulation of the world ocean circulation [PDF]

A multi-level model, based on the primitive equations, is developed for simulating the temperature and velocity fields produced in the world ocean by differential heating and surface wind stress. The model ocean has constant depth, free slip at the lower
Han, Y. J., Mintz, Y., Takano, K.
core   +1 more source