Results 131 to 140 of about 1,625,991 (316)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Structured Surfaces, Measurements & Characterization

The most important physical phenomena involving exchange of energy and/or signal transmission take place on surfaces. And surface topography or texture play a very important role in functional performance, like wetting, reflection, etc, as in Table 1 and
Wang, Jian, Blunt, Liam, Leach, Richard K., Jiang, Xiang   +3 more
core  

The spinor representation of constant mean curvature one surfaces in the Hyperbolic space

, 1970
We review and comment on some aspects of the spinor representation for constant mean curvature one surfaces in hyperbolic space developed by Bobenko-Pavlyukevich-Springborn in [1].
Nicolodi, Lorenzo, Musso, Emilio, Nicolodi, L., MUSSO E, NICOLODI L.   +4 more
core   +1 more source

Virucidal and Antibacterial Chitosan–NanoCu Film-Coating-Based Technology: Complete Analysis of Its Performance on Various Surfaces

Viruses
The transmission of viruses and bacteria via surfaces remains a persistent challenge for healthcare systems, leading to high public health costs and significant environmental impact due to the widespread use and disposal of single-use products.
Victoria Belen Ayala-Peña, María Julia Martin, Jessica Otarola, Florencia Favatela, Jimena Soledad Gonzalez, Ana Lucía Conesa, Cybele Carina García, Claudia Soledad Sepúlveda, Vera Alejandra Alvarez, Verónica Leticia Lassalle   +9 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

3D freeform surfaces from planar sketches using neural networks

, 2006
A novel intelligent approach into 3D freeform surface reconstruction from planar sketches is proposed. A multilayer perceptron (MLP) neural network is employed to induce 3D freeform surfaces from planar freehand curves.
Terchi, A, Khan, U, Wright, D, Lim, S, Khan, Usman, Terchi, Abdelaziz, Wright, David, Qin, S F, Usman Khan, Abdelaziz Terchi, Qin, Sheng-feng, Sheng-Feng Qin, Lim, Sungwoo, David Wright, Sungwoo Lim   +14 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Surfaces.

, 2017
'Surfaces' - A solo exhibition of recent work at the New Court gallery Repton.
Robinson, C.
core  

The Surface Evolver

Experimental Mathematics, 1992
The Surface Evolver is a computer program that minimizes the energy of a surface subject to constraints. The surface is represented as a simplicial complex. The energy can include surface tension, gravity and other forms. Constraints can be geometrical constraints on vertex positions or constraints on integrated quantities such as body volumes.
openaire   +2 more sources