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Surfactants and atherogenesis

Medical Hypotheses, 1977
In previous publications (1,2) the hypothesis was put forward that atheroma is caused by some pathogen or metabolic fault which impairs the transportability of cholesterol in the plasma. The lipoproteins containing the faulty metabolites are assumed to be incapable of traversing the capillary endothelium and continue to circulate uselessly in the blood
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Surfactant–Amino Acid and Surfactant–Surfactant Interactions in Aqueous Medium: a Review

Applied Biochemistry and Biotechnology, 2015
An overview of surfactant-amino acid interactions mainly in aqueous medium has been discussed. Main emphasis has been on the solution thermodynamics and solute-solvent interactions. Almost all available data on the topic has been presented in a lucid and simple way.
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BIOLOGY OF SURFACTANT

Clinics in Perinatology, 2001
Surfactant is a metabolically active assembly of phospholipids and surfactant-specific proteins that is essential for normal lung mechanics. The surfactant proteins SP-A and SP-D also have important innate host defense functions. Surfactant metabolism in the developing lung differs from the adult lung by having slower kinetics of secretion with a ...
A H, Jobe, M, Ikegami
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Surfactant catabolism

Respirology, 2006
Abstract:  Alveolar pulmonary surfactant is a complex of macromolecular aggregates composed of phospholipids and surfactant proteins (SP) that is essential for maintenance of normal lung function. The importance of surfactant homeostasis is recognized in the patients and the animal models with pulmonary disease, although the mechanisms of surfactant ...
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Surfactants and the environment

International Journal of Cosmetic Science, 1984
SynopsisAs a result of their use in detergents and personal products and their subsequent disposal, anionic surfactants may achieve a wide distribution in the environment. It is therefore important to assess the hazard that this use might present to the environment.In order to do this it is necessary to estimate the highest concentrations which are ...
P A, Gilbert, R, Pettigrew
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Aerosolized surfactants

Current Opinion in Pediatrics, 2007
To present existing data on the potential use of aerosolized surfactants for treatment of neonatal respiratory distress syndrome in the era of noninvasive ventilatory support.Current surfactant therapy requires endotracheal intubation and application of positive pressure ventilation.
Jan, Mazela   +2 more
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Surfactant Metabolism

Clinics in Perinatology, 1993
Based on these metabolic studies of surfactant lipids in term lambs, in preterm lambs not treated with surfactant, and in preterm lambs that have been surfactant-treated, the following is a synthesis of the overall metabolism of surfactant. Preterm surfactant-deficient lungs seem to have all the synthetic and secretory pathways for surfactant ...
A H, Jobe, M, Ikegami
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Surfactant in Surgery

Surgical Clinics of North America, 1974
The observed changes in surfactant, the surface-active material which lines the alveoli of mammalian lungs, suggest a secondary effect rather than causation, which is no less important to pulmonary function. In the complex interdependency of many factors permitting adequate gas exchange, it appears that pulmonary surfactant has a significant yet ...
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Pulmonary surfactant

Journal of Applied Physiology, 1982
Pulmonary surfactant reduces the surface tension of the alveolar air-liquid interface, thereby providing mechanical stability and preventing alveolar atelectasis. More than 50% of surfactant is dipalmitoyl phosphatidylcholine, a material that is capable of reducing the surface tension of the alveolar interface to uniquely low values.
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Pulmonary surfactant

Canadian Journal of Biochemistry and Cell Biology, 1984
The mammalian lung is stabilized by a specialized material, the pulmonary surfactant, which acts by reversibly reducing the surface tension at the air–liquid interface of the lung during breathing. Pulmonary surfactant contains approximately 90% lipid and 10% proteins. Dipalmitoyl phosphatidylcholine, the major lipid component, appears to be primarily
F, Possmayer   +3 more
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