Results 161 to 170 of about 2,292,861 (284)

In the Wake of a Report

, 2018
**TW: Sexual Assault Earlier in the semester, many students and professors gathered in the Junction from 10 am until well into the evening to watch as Christine Blasey Ford and now Supreme Court Justice Brett Kavanaugh were each questioned at length.
Holden, Rebecca L.
core  

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

The effect of evening vs. morning medication on morning blood pressure surge. [PDF]

Sci Rep
Zhang XJ, Yan Y, Liu YJ, Liu Q, Jesiser C, Yang XY, Cao YX, Cao L.   +7 more
europepmc   +1 more source

When You Love Physics, But Physics Doesn\u27t Love You

, 2019
I am a physics major. Or at least, I was. My class year was an average-sized group of majors; mostly cis men, mostly people I do not feel comfortable around.
Perry, Anna K.
core  

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

Advanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin, Hong Xiao, Shuai Fan, Kaimin Cai, Yanteng Xu, Xinwen Wang, Guanhong Chen, Chuandong Lang, Xinsheng Peng, Mingqiang Li, Yuhu Dai   +10 more
wiley   +1 more source

Emergency Departments as Early Clinical Sentinels and the Final Operational Buffer. [PDF]

J Acute Med
Chi CH.
europepmc   +1 more source

This Is How You Lose Me

, 2019
I liked the intimate setting of the class at first. The silence before the professor walked in. The cramped room. It always smelled like citrus cleaning products. Some hair gel mixed in there, too.
Cincotta, Anna
core  

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

Advanced Science, EarlyView.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu, Xiyan Liao, Limin Xie, Xiaoxiao Sun, Luodi Jing, Qin Zeng, Hongwei Jiang, Haowei Zhang, Lei Li, Fanqi Wang, Dandan Wang, Ying Mei, Yujin Din, Jianfeng Song, Wufuer Aini, Hui Zhou, Wanqin Xie, Helong Dai, Wei Liu, Joey Liu, Yan Cheng, Feng Liu, Willa A. Hsueh, Tuo Deng   +23 more
wiley   +1 more source

A Strategy for Surge Management: Senior Residents on the Admitting Frontlines. [PDF]

J Community Hosp Intern Med Perspect
Saifuddin H, Yockey O, Pichot R, Brainard G, Labay S, Wang MS.   +5 more
europepmc   +1 more source

An Open Letter to Netflix

, 2013
If there is one thing that I will be absolutely ashamed in admitting to you, it’s that I love television. Love it. Not in a turn-it-on-watch-whatever-all-TV-rocks kind of way, but in an I’m-overly-obsessed-with-15-shows-at-a-time kind of way, to the ...
Rupert, Elizabeth A.
core