Results 201 to 210 of about 2,517,198 (384)

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Lady Gaga, Racist Jokes, and Other Pet Peeves

, 2013
When I was a kid, my sister would whistle whenever I entered a room because she knew that it bothered me. I picked up on this trick, and I use it even now that I’m older.
Center for Public Service,
core  

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Fearless: Nadejiah Towns

, 2013
This week we would like to recognize Nadejiah Towns ’15 as a fearless fighter against poverty. This summer she has served as a Heston intern for the South Central Community Action Program (SCCAP) and has spent the majority of her time with the Work Ready
Towns, Nadejiah Z.
core  

Efficacy of Neural Tissue Mobilization Versus Cervical Mobilization Along with Manualtraction and Surged Faradic Current on Pain, Disability and Rom in Chronic Cervical Radiculopathy Patients

, 2023
Kartik Chhonker, Kalpana Jain, Namrata Srivastava   +2 more
openalex   +2 more sources

PEDOT:PSS—A Key Material for Bioelectronics

Advanced Science, EarlyView.
PEDOT:PSS ‐ Poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate ‐ is typically processed from water dispersions to form multifunctional and multidimensional constructs with tunable electronic and ionic conductivity. Throught processing engineering, PEDOT:PSS is intergrated in bioelectronic devices that operate efficiently in physiological conditions
Alan Eduardo Ávila Ramírez, David Pieter van der Laan, Mustafeez Bashir Shah, Liwen Wang, Erica Zeglio, Achilleas Savva   +5 more
wiley   +1 more source

Fearless: Aleksandra Petkova

, 2013
Consistently serving the campus community, conducting new research in psychology, and leading younger students to realizations about their own roles in fighting for social Justice, Aleksandra Petkova ’14 has fearlessly pursued opportunities to promote ...
Petkova, Aleksandra V.
core  

Glacier velocity and surge detection in the Karakoram region, Pakistan: using remotely sensed data with cross-correlation feature tracking

Zhijie Zhang, Zahoor Ahmad, Shengqin Xiong, Wanchang Zhang   +3 more
openalex   +1 more source

A Quantum Framework for Protein Binding‐Site Structure Prediction on Utility‐Level Quantum Processors

Advanced Science, EarlyView.
This study presents a hybrid quantum‐classical framework for accurate prediction of protein structures on utility‐level quantum processors. We evaluate the practical application of the Variational Quantum Eigen‐solver (VQE) in protein structure prediction and demonstrate its superiority over state‐of‐the‐art deep learning methods in molecular docking ...
Yuqi Zhang, Yuxin Yang, William Martin, Kingsten Lin, Zixu Wang, Cheng‐Chang Lu, Weiwen Jiang, Ruth Nussinov, Joseph Loscalzo, Qiang Guan, Feixiong Cheng   +10 more
wiley   +1 more source

Correction: Omicron surge impact on acute kidney injury in ICU patients: A study using the ISARIC COVID-19 database. [PDF]

PLoS One
Dai D, Gois PF, Wainstein M, Ghadimi M, Spyrison N, Granado RC, Shrapnel S, Pole JD, ISARIC Characterization Group.   +8 more
europepmc   +1 more source