Results 211 to 220 of about 265,562 (294)

STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches

open access: yesAdvanced Science, EarlyView.
This schematic outlines STING trafficking and signaling via coat protein II (COPII)‐mediated endoplasmic reticulum (ER) export. Following cyclic GMP‐AMP (cGAMP) stimulation, TANK‐binding kinase 1 (TBK1) activates on COPII vesicles, partially dissociating into the cytosol to phosphorylate ER‐localized STING, creating pSGME/pFS COPII‐sorting motifs ...
Yanan Nan   +10 more
wiley   +1 more source

Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke

open access: yesAdvanced Science, EarlyView.
Delayed transplantation of human iPSC‐derived neural progenitor cells (NPCs) enhances graft survival, proliferation, and axonal sprouting after stroke. Using bioluminescence imaging and histology in a mouse model of stroke, it is shown that NPC delivery at 7 days post‐stroke is more effective than acute transplantation, highlighting the importance of ...
Rebecca Z Weber   +6 more
wiley   +1 more source

Nanosensitizer for Cancer Radioimmunotherapy via Anti‐IL‐35 Blockade Boosted Innate Immunity Activation

open access: yesAdvanced Science, EarlyView.
Zheng et al. designed a tumor microenvironment (TME)‐responsive nanosystem, HmBMH@MSA‐2. It targets tumors, releases MSA‐2 and Mn ions in high glutathione (GSH) conditions, achieving STING agonist delivery and MRI. The nanosystem promotes chemodynamic therapy (CDT), achieves radiosensitization, and activates the cGAS‐STING pathway.
Yinfei Zheng   +11 more
wiley   +1 more source

Current Approaches and Challenges in Advanced Oxidation Processes for Nanoplastic Degradation

open access: yesAdvanced Science, EarlyView.
This review explores recent progress in advanced oxidation processes (AOPs) for the degradation of nanoplastics (NPs) in water. It presents a comparative assessment of key AOP technologies and identifies current limitations in analytical methods and treatment efficiency.
Arezou Fazli   +2 more
wiley   +1 more source

Ubiquity of Rotational Symmetry Breaking in Superconducting Films, From Fe(Te,Se)/Bi2Te3 to Nb, and the Effect of Measurement Geometry

open access: yesAdvanced Science, EarlyView.
In‐plane magneto‐transport measurement is a popular method to probe the nematicity of unconventional superconductors. However, with this scheme, nematic behaviors are observed not only for an unconventional superconductor, Fe(Te,Se)/Bi2Te3 heterostructure, but also for an isotropic conventional superconductor, Nb.
Debarghya Mallick   +3 more
wiley   +1 more source

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