Results 261 to 270 of about 2,445,443 (387)

Hippocampal Chandelier Cells Modulate Seizure Susceptibility and Severity

open access: yesAdvanced Science, EarlyView.
The axon initial segment (AIS), crucial for action potential initiation, serves as a prime locus for controlling network activity. Chandelier Cells (ChCs), evolved in the mammals, intricately target AISs, acting as gatekeepers for neuronal firing. Diminishing ChC input makes animals more prone to developing seizures, whereas fortifying this connection ...
Yang Li   +7 more
wiley   +1 more source

Replacing BPA: Structural Substitutes BPAF Binding to the Progesterone Receptor Elevates Breast Cancer Risk

open access: yesAdvanced Science, EarlyView.
This study demonstrates that bisphenol analogues, particularly BPAF, bind to progesterone receptor, promoting breast cancer cell proliferation, migration, and mammary tumor growth, indicating that bisphenol A substitutes may pose equal or greater health risks.
Xiaotong Ji   +8 more
wiley   +1 more source

Pakistan's sudden HIV surge: a national crisis with international implications. [PDF]

open access: yesAnn Med Surg (Lond)
Ali MR   +3 more
europepmc   +1 more source

A Synergistic Complexation‐Encapsulation Paradigm Enables Unprecedented Radioactive Remediation

open access: yesAdvanced Science, EarlyView.
A novel HDEHP‐APG eutectic mixture‐based detergent is developed that achieves highly efficient decontamination of Am through a synergistic complexation‐encapsulation mechanism. Remarkably, such a detergent effectively removes radionuclides across a wide range of oxidation states (+I to +VII), demonstrating exceptional versatility.
Qilong Tang   +4 more
wiley   +1 more source

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