Results 121 to 130 of about 116,145 (312)

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Accuracy of Patient-Specific Instrumentation for Bone Tumor Resection within the pelvis: 1st study of 11 patients [PDF]

open access: yes, 2014
Introduction Pelvic bone tumor resection is challenging due to complex geometry, limited visibility and restricted working space of the pelvis. Accurate resection in safe margin is required to reduce the risk of local recurrence.
Cartiaux, Olivier   +4 more
core  

Computer assisted jaw reconstruction

open access: yes, 2021
Reconstruction of the jaws after tumour ablation surgery requires understanding of craniofacial anatomy and dental occlusion in order to restore function and aesthetics.
Choi, WWS
core  

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Tibiofemoral Joint Kinematics

open access: yes, 2013
This book discusses the full range of current applications of computer-assisted surgery and robotics in the field of knee surgery, and also considers potential future applications.
Colle F   +8 more
core   +1 more source

Detection, identification and audification of pulsatile structures using proximal data acoustic sensing

open access: yesCurrent Directions in Biomedical Engineering
This work demonstrates the detection and identification of pulsatile activity using proximal vibroacoustic sensing in laparoscopic instruments. A controlled setup simulating vascular pulsations was used to evaluate two signal processing methods ...
Espejo Diego   +4 more
doaj   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Navigation for resection of pelvic sarcomas and reconstruction

open access: yes, 2011
Purpose of the study: Resection of sarcomas from the pelvis is particularly difficult because of the risk of injury to the vascular and neurological structures and the complex helicoidal anatomy of the iliac bone.
Cartiaux, Olivier   +5 more
core  

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

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