Results 51 to 60 of about 328,614 (292)
BackgroundTraditionally, synchronous liver resection (LR), cytoreductive surgery (CRS), and hyperthermic intraperitoneal chemotherapy for colorectal liver and peritoneal metastases have been contraindicated.
Sara Di Carlo +13 more
doaj +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Stereotactic guidance for navigated percutaneous sacroiliac joint fusion. [PDF]
Arthrodesis of the sacroiliac joint (SIJ) for surgical treatment of SIJ dysfunction has regained interest among spine specialists. Current techniques described in the literature most often utilize intraoperative fluoroscopy to aid in implant placement ...
Kim, Kee D +4 more
core +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Advances in general surgical laparoscopy [PDF]
Minimally invasive surgery has been with us for the past century. The lasl thirty years have seen an exponential growth in the development of laparoscopic techniques which allow major surgery to be performed through smaller incisions and less ...
Abela, Jo Etienne
core
Image-guided Simulation of Heterogeneous Tissue Deformation For Augmented Reality during Hepatic Surgery [PDF]
International audienceThis paper presents a method for real-time augmentation of vas- cular network and tumors during minimally invasive liver surgery.
Berger, Marie-Odile +5 more
core +3 more sources
Minimally invasive parathyroid surgery [PDF]
This paper was written by members of the International Head and Neck Scientific Group ( http://www.IHNSG.com ).
Owen, Randall P. +4 more
openaire +3 more sources

