Results 51 to 60 of about 3,324,875 (313)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Retención dentaria

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2015
En el síndrome de retención dentaria los dientes quedan encerrados dentro de los maxilares, manteniendo la integridad de su saco pericoronario fisiológico.
Delarays Ossani Pérez Alfonso, Yaima de Los Ángeles Hidalgo Torres, Omelio Fontaine Machado   +2 more
doaj  

Anatomical Positions of Mesially/Horizontally Impacted Mandibular Third Molars are Significant Predictors for Distal Caries in Adjacent Second Molars

International Journal of Dentistry, 2022
Background. Prevalence of distal caries in mandibular second molars (M2Ms) and its relationship with impacted condition of the adjacent mandibular third molars (M3Ms) have been reported in some studies.
Son Hoang Le, Nhut Minh Nguyen, Ngoc Thi-Bao Nguyen, Ly Thi-Bich Nguyen   +3 more
doaj   +1 more source

Oral lichen sclerosus: Diagnosis and conservative approach

, 2021
School of Dentistry Oral Oncology Center São Paulo State University (UNESPDepartment of Diagnosis and Surgery School of Dentistry São Paulo State University (UNESPDepartment of Oral Diagnosis Piracicaba Dental School University of Campinas (UNICAMPDental
Luciana Estevam Simonato, Oslei Paes de Almeida, Glauco Issamu Miyahara, Vargas, Pablo Agustin, Saygo Tomo, Simonato, Luciana Estevam, Pablo Agustin Vargas, Tomo, Saygo [UNESP], Miyahara, Glauco Issamu [UNESP], John Lennon Silva Cunha, de Almeida, Oslei Paes, Cunha, John Lennon Silva   +11 more
core   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

Arthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni, Chloe Shields, Rohit Muralidhar, Shreya Bhatt, Alan Baer, Robert Fox, Sara S. McCoy, Anat Galor   +7 more
wiley   +1 more source

Oral Malignant Melanoma: The Amsterdam Experience

, 2007
Purpose: The purpose of this study was to evaluate the clinical, pathological, and therapeutic experience of a group of patients with primary oral malignant melanoma (OMM) in Amsterdam, The Netherlands. Patients and Methods: Fourteen patients (5 males, 9
van der Waal, Isaäc, Leemans, C. René, Meleti, Marco, Mooi, Wolter J.   +3 more
core   +1 more source

Oral surgery waiting lists at an Australian university dental school

, 2022
Objective: The aim of this study was to investigate the waiting times experienced by patients referred to an Australian University oral surgery clinic over a 2-year period.
Peter Reher, Ngu, ACS, Sitanshu Arora, Anthony C. S. Ngu, Reher, P, Arora, S   +5 more
core   +1 more source

Krokodil (Desomorphine)-induced osteonecrosis of the maxilla: a case report and literature review

Journal of Oral Medicine and Oral Surgery, 2019
Introduction: Desomorphine is an opioid formerly used to treat acute pain. It is simple to manufacture, which has recently led to an increase in its clandestine production under the name “Krokodil”.
Sergent Jean-François, Bader Gérard, Hamon Julien, Peigne Lucie, Lejeune Sophie   +4 more
doaj   +1 more source

Hard and Soft Tissue Augmentation with Single-Implant Restoration in the Esthetic Zone

Case Reports in Dentistry, 2021
The removal of the central incisor of the upper jaw is a challenging process, since the restoration of a single implant in the esthetic zone is of great responsibility.
Igor Ashurko, Nataliia Blagushina, Anisa Borodiy, Mary Magdalyanova   +3 more
doaj   +1 more source