Results 121 to 130 of about 3,257,956 (354)

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

open access: yesAdvanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv   +13 more
wiley   +1 more source

Treatment of complex regional pain syndrome using free-flap surgery: a case report

open access: yesJournal of Pain Research, 2017
Dong-Kyo Seo,1 Ho-Seong Lee,2 Joon Pio Hong,3 Jeong-Ho Seo,4 Jin Woo Shin5 1Department of Orthopedic Surgery, GangNeung Asan Hospital, College of Medicine, University of Ulsan, GangNeung-si, South Korea; 2Department of Orthopedic Surgery, 3Department of ...
Seo DK, Lee HS, Hong JP, Seo JH, Shin JW
doaj  

3D printing in orthopedic surgery

open access: yes, 2023
The advent of 3D printing in orthopedics has allowed the creation of patient-specific anatomical models, custom-made implants, surgical guides and even bioprinted tissues. This technology has the potential to revolutionize preoperative planning, surgical
Villafañe, Jorge H.   +4 more
core   +1 more source

Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment

open access: yesAdvanced Science, EarlyView.
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen   +15 more
wiley   +1 more source

Factors influencing the selection criteria of Saudi board orthopedic surgery applicants: a national survey of program directors

open access: yesBMC Medical Education
Background Annually, medical students vie to secure a seat with an orthopedic residency program. This rigorous competition places orthopedic surgery as one of the most competitive specialties in the medical field.
Suhail S. AlAssiri   +8 more
doaj   +1 more source

PROGRESS IN ORTHOPEDIC SURGERY [PDF]

open access: yesArchives of Surgery, 1921
TUBERCULOSIS Treatment of Paraplegia in Pott's Disease by Puncture of Spinal Abscess.—Calve1believes that paraplegias are less likely to recover under nonoperative treatment in adults than in children. He reminds us that they occur almost exclusively in those cases in which the lesion is located in the dorsal vertebrae, and he thinks the common cause ...
openaire   +2 more sources

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

open access: yesAdvanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao   +10 more
wiley   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

open access: yesAdvanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun   +14 more
wiley   +1 more source

Arthroscopically Confirmed Complete Healing of Anterior Cruciate Ligament Avulsion Fracture Following Four-Corner Pullout Repair Using Ultrahigh-Molecular-Weight Polyethylene Tapes: A Case Report

open access: yesCase Reports in Orthopedics
We report a case of tibial insertion avulsion fracture of the anterior cruciate ligament (ACL). A 10-year-old boy who fell from a skateboard was diagnosed with a tibial insertion avulsion fracture of the ACL and was treated arthroscopically.
Toshiki Kohara   +10 more
doaj   +1 more source

History of Orthopedic Surgery in Utah since World War II

open access: yes, 2008
Video presentation by Dr Wallace Hess discussing the history of orthopedic surgery in Utah from its early days before the second world war and ...

core  

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