Results 61 to 70 of about 263,732 (260)

Kaempferol Attenuates Spaceflight‐Associated Knee Cartilage Degradation by Targeting NOX4‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
We have shown that both simulated and actual spaceflight contribute to cartilage degradation in the knees of mice. Using RNA sequencing and bioenergetic profiling, we identified NADPH oxidase 4 (NOX4) as a key factor driving these changes. Additionally, we found that kaempferol, a naturally occurring flavonoid that binds directly to NOX4, reduces ...
Yuesong Yin, Ruiling Xu, Meagan J. Makarczyk, Jia‐Jun Liu, Silvia Liu, Matthew Z. Shi, Roberta Di Carlo, Michael F. Almeida, Alex Garris, Sarah Day, Rebekah Sanchez‐Hodge, Jonathan C. Schisler, Aleeza H. Zilberman, Noah G. Allen, Angela J. Kubik, Elizabeth A. Blaber, Arnold Z. Olali, Wanqing Xie, Douglas C. Wallace, Christopher E. Mason, Peter G. Alexander, Giuseppe Intini, Afshin Beheshti, Hang Lin   +23 more
wiley   +1 more source

Treatment of complex regional pain syndrome using free-flap surgery: a case report

Journal of Pain Research, 2017
Dong-Kyo Seo,1 Ho-Seong Lee,2 Joon Pio Hong,3 Jeong-Ho Seo,4 Jin Woo Shin5 1Department of Orthopedic Surgery, GangNeung Asan Hospital, College of Medicine, University of Ulsan, GangNeung-si, South Korea; 2Department of Orthopedic Surgery, 3Department of ...
Seo DK, Lee HS, Hong JP, Seo JH, Shin JW
doaj  

ORTHOPEDIC SURGERY IN THE AGING POPULATION: CHALLENGES AND FUTURE DIRECTIONS

Tạp chí Sức khỏe và Lão hóa (Journal of Health and Aging)
The rapid aging of the global population has led to a substantial rise in the demand for orthopedic surgery among elderly patients, particularly for hip, knee, and shoulder arthroplasty.
Tran Quoc Doanh, Ho Bui Dieu Linh, Tran Khoi Luan, Vu Quoc Hung, Nguyen Van Binh, Tran Duc Tai, Dang Thi Hai An, Doan Van Khue, Le My Huyen, Nguyen Anh Sang   +9 more
doaj   +1 more source

PROGRESS IN ORTHOPEDIC SURGERY [PDF]

Archives of Surgery, 1921
TUBERCULOSIS Treatment of Paraplegia in Pott's Disease by Puncture of Spinal Abscess.—Calve1believes that paraplegias are less likely to recover under nonoperative treatment in adults than in children. He reminds us that they occur almost exclusively in those cases in which the lesion is located in the dorsal vertebrae, and he thinks the common cause ...
openaire   +2 more sources

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source

Osteopathic Student Matriculation Trends in Surgical Subspecialties (2016-2024): A Systematic Review

Journal of Medical Education and Curricular Development
Background There is a paucity of data on trends of osteopathic medical students (OMS) matriculating into surgical specialties since the installation of the single U.S.
Bridgette Kielhack, Selena K. Cholak, Virgil K. DeMario, Vaishnavi J. Patel, Devki Patel, Kimberly Toumazos, Mark Quiring, Young Son, John Etlinger   +8 more
doaj   +1 more source

Orthopedic treatment of the lower limbs in spastic paralysis

Brain Science Advances, 2020
Spastic paralysis of the limb mainly results from the central lesion, in which spastic cerebral palsy is the common cause. Due to durative muscle spasm in spastic cerebral palsy, it is often accompanied by the formation of secondary musculoskeletal ...
Xiaohong Mu, Bowen Deng, Jie Zeng, Houjun Zhang, Yi Zhao, Qi Sun, Jie Xu, Le Wang, Lin Xu   +8 more
doaj   +1 more source

Deconstruction of Human Age‐Related Cataract Capsules Defines Aging

Advanced Science, EarlyView.
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang, Ziyang Tong, Chunmei Fan, Silong Chen, Jiarui Guo, Jianghua Hu, Ke Yao, Zi Yin, Xiao Chen, Yibo Yu   +9 more
wiley   +1 more source

Factors influencing the selection criteria of Saudi board orthopedic surgery applicants: a national survey of program directors

BMC Medical Education
Background Annually, medical students vie to secure a seat with an orthopedic residency program. This rigorous competition places orthopedic surgery as one of the most competitive specialties in the medical field.
Suhail S. AlAssiri, Alwaleed A. Alshahir, Sami I. Al Eissa, Fahad H. Al Helal, Faisal M Konbaz, Majed S. Abaalkhail, Rayed M. Al Jehani, Abdullah F. Mohabbat, Khalid A. AlSheikh   +8 more
doaj   +1 more source

AI‐Assisted Engineering of Glycyrrhizic Acid/Simvastatin Nanocrystals for Multifunctional Treatment of Bacterial Osteomyelitis

Advanced Science, EarlyView.
Through AI‐assisted screening from FDA‐approved API to overcome the limitations of bacterial osteomyelitis treatment, glycyrrhizic acid and simvastatin are identified as a multifunctional combination capable of self‐assembling into mechanism‐targeting nanocrystals that effectively neutralize reactive oxygen species, suppress M1 macrophage polarization,
Yu Han, Yao Zhao, Chengbo Yang, Miao Niu, Jun Dai, Quanxin Ning, Kai Xiao, Jinzheng Liang, Wensheng Zhang, Liang Wang, Dan Shao, Dongsong Li   +11 more
wiley   +1 more source